61045-33-8 Usage
Description
(2R,3R)-diethyl 1,4-dioxaspiro[4.5]decane-2,3-dicarboxylate is a chemical compound characterized by its unique spirocyclic ester structure, featuring a dioxane ring and two carboxylate groups. With the molecular formula C14H22O6, this compound possesses a spiro skeleton that includes a bridgehead carbon atom, to which diethyl ester groups are attached. Its distinctive structure and reactivity make it a compound of interest in various research fields, particularly in medicinal chemistry.
Uses
Used in Pharmaceutical Synthesis:
(2R,3R)-diethyl 1,4-dioxaspiro[4.5]decane-2,3-dicarboxylate is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the formation of complex molecular structures. Its unique spirocyclic ester configuration allows for the creation of novel drug candidates with potential therapeutic applications.
Used in Organic Chemistry Research:
In the field of organic chemistry, (2R,3R)-diethyl 1,4-dioxaspiro[4.5]decane-2,3-dicarboxylate serves as a valuable compound for exploring new reaction pathways and understanding the reactivity of spirocyclic systems. Its potential applications in this area may lead to the development of new synthetic methods and the discovery of additional compounds with useful properties.
Used in Medicinal Chemistry:
(2R,3R)-diethyl 1,4-dioxaspiro[4.5]decane-2,3-dicarboxylate is used as a key building block in the design and synthesis of new bioactive molecules for medicinal chemistry. Its incorporation into drug candidates can potentially enhance their pharmacological properties, such as selectivity, potency, and bioavailability, leading to more effective treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 61045-33-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,0,4 and 5 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 61045-33:
(7*6)+(6*1)+(5*0)+(4*4)+(3*5)+(2*3)+(1*3)=88
88 % 10 = 8
So 61045-33-8 is a valid CAS Registry Number.
61045-33-8Relevant articles and documents
Novel tartrate-derived guanidine-catalyzed highly enantio- and diastereoselective Michael addition of 3-substituted oxindoles to nitroolefins
Zou, Liwei,Bao, Xiaoze,Ma, Yuanyuan,Song, Yuming,Qu, Jingping,Wang, Baomin
supporting information, p. 5760 - 5762 (2014/05/20)
The Michael addition of 3-substituted oxindoles to nitroolefins was catalyzed by a novel tartrate-derived guanidine in high yield with excellent diastereo- and enantioselectivity. This method showed an extraordinarily broad substrate scope in terms of both reaction partners. the Partner Organisations 2014.
Stereoselective total synthesis of synparvolide B and epi-synparvolide A
Srihari,Vijaya Bhasker,Bal Reddy,Yadav
scheme or table, p. 2420 - 2424 (2009/08/07)
Stereoselective total synthesis of synparvolide B and epi-synparvolide A has been achieved following a convergent approach. Noyori asymmetric Transfer Hydrogenation of ketone and Wadsworth-Emmons olefination reaction are the key steps involved.
Synthesis of 1-Deoxy-D-galactohomonojirimycin via Enantiomerically Pure Allenylstannanes
Achmatowicz, Michal,Hegedus, Louis S.
, p. 2229 - 2234 (2007/10/03)
1-Deoxy-D-galactohomonojirimycin was synthesized in seven steps from optically pure allenylstannane 4 and L-lactate-derived aldehyde 5 in 48% overall yield. The key step was the Lewis acid catalyzed reaction of 4 and 5 to give the syn-amino alcohol in exc
