61054-29-3Relevant articles and documents
Palladium-Catalyzed Direct C-H Arylation of Isoxazoles at the 5-Position
Shigenobu, Masashi,Takenaka, Kazuhiro,Sasai, Hiroaki
supporting information, p. 9572 - 9576 (2015/08/11)
A palladium-catalyzed direct arylation of isoxazoles with aryl iodides has been achieved. The C-H bond at the 5-position is activated selectively to give coupling products in moderate to good yields. This direct arylation was applied to the synthesis of a spiro-type chiral ligand, which proved to be most effective to the palladium-catalyzed tandem cyclization of a dialkenyl alcohol.