61057-42-9Relevant articles and documents
Synthesis and antimalarial activity of some triphenyltin(IV) aminobenzoate compounds against Plasmodium falciparum
Fenska, Mona Dwi,Hadi, Sutopo,Naseer, Muhammad Moazzam,Noviany, Noviany,Satria, Heri,Simanjuntak, Wasinton
, p. 256 - 260 (2021/10/29)
This paper presents antimalarial activity of several triphenyltin(IV) aminobenzoate compounds synthesized from the reaction of triphenyltin(IV) hydroxide with 2-, 3-, and 4-aminobenzoic acid. The activity of the compounds as anti-malaria agents was evaluated using Plasmodium falciparum, and demonstrated that the compounds have about the same IC50 with that of chloroquine (2×10-3 μg/mL) applied as the positive control. The result also showed that the Plasmodium is non-resistent to the compounds synthesized, which is the opposite to chloroquine.