61065-16-5

Basic information

• Product Name: 8-benzyl-9,10-dimethoxy-5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline
• CAS NO: 61065-16-5
• Molecular Formula: C₂₇H₂₇NO₄
• Molecular Weight: 429.5076
• Mol File: 61065-16-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 545.9°C at 760 mmHg
• Flash Point: 151.2°C
• Density: 1.3g/cm³
• Vapor Pressure: 5.66E-12mmHg at 25°C
• Refractive Index: 1.667
• CAS DataBase Reference: 8-benzyl-9,10-dimethoxy-5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 8-benzyl-9,10-dimethoxy-5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline(61065-16-5)
• EPA Substance Registry System: 8-benzyl-9,10-dimethoxy-5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline(61065-16-5)

Safety Data

• Hazardous Substances Data: 61065-16-5(Hazardous Substances Data)

Upstream product

• 61065-15-4 8-benzyl-9,10-dimethoxy-5,8-dihydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline 
• 71266-80-3 8-benzyl-9,10-dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolinylium; bromide 
• 549-21-3 oxyberberine 
• 29074-38-2 canadine 

Downstream Products

• 1099738-77-8 (+/-)-8-benzyl-9,10-dimethoxy-5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline hydrochloride 

Relevant articles and documents

From berbines to protopines: Regiocontrolled Hofmann elimination/ hydroboration/oxidation of N-substituted berbinium salts

An improved synthetic approach to protopines based on the sequential Hofmann elimination, hydroboration and oxidation of N-(arylmethyl)berbinium salts has been designed. By using berberine chloride as the starting material, this sequence of reactions has provided two new nonnatural protopines, N-benzyl-N-nordihydroallocriptopine and N-(p-methoxybenzyl)-N- nordihydroallocriptopine and the natural allocriptopine. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.

Chemistry of 8-chloroberberine

-