61083-59-8 Usage
Description
2-(TRIPHENYLPHOSPHONIO)ETHYL CHLORO-, also known as 2-(Triphenylphosphonio)ethyl Chloroformate Chloride, is a chemical compound that is widely used in the field of peptide chemistry. It is characterized by its ability to protect amino and hydroxyl functional groups, which is crucial for the synthesis and modification of peptides.
Uses
Used in Peptide Chemistry:
2-(TRIPHENYLPHOSPHONIO)ETHYL CHLOROis used as a protecting agent for amino and hydroxyl functional groups in peptide chemistry. The protection of these functional groups is essential to prevent unwanted side reactions during the synthesis and modification of peptides, ensuring the desired product is obtained with high purity and yield.
The use of 2-(TRIPHENYLPHOSPHONIO)ETHYL CHLOROin peptide chemistry is particularly important in the following applications:
1. Synthesis of Peptides and Peptide Derivatives:
In the synthesis of peptides and their derivatives, the protection of amino and hydroxyl groups is crucial to avoid unwanted side reactions, such as racemization, oxidation, or hydrolysis. 2-(TRIPHENYLPHOSPHONIO)ETHYL CHLOROserves as an effective protecting agent, allowing chemists to selectively modify specific functional groups in a controlled manner.
2. Solid-Phase Peptide Synthesis (SPPS):
Solid-phase peptide synthesis is a widely used technique for the production of peptides and proteins. 2-(TRIPHENYLPHOSPHONIO)ETHYL CHLOROplays a vital role in this process by protecting the amino and hydroxyl groups of the growing peptide chain, ensuring the successful assembly of the desired peptide sequence.
3. Peptide Modification and Conjugation:
Peptide modification and conjugation are essential for the development of bioactive peptides, drug delivery systems, and peptide-based therapeutics. 2-(TRIPHENYLPHOSPHONIO)ETHYL CHLOROis used to protect specific functional groups during these processes, allowing for the selective introduction of various modifications, such as biotin, fluorescent tags, or other functional moieties.
4. Pharmaceutical Research and Development:
In the pharmaceutical industry, 2-(TRIPHENYLPHOSPHONIO)ETHYL CHLOROis used to protect amino and hydroxyl groups during the synthesis of peptide-based drugs. This protection is crucial for maintaining the stability, solubility, and bioavailability of the final drug product, as well as for minimizing potential side effects.
5. Research in Biochemistry and Molecular Biology:
2-(TRIPHENYLPHOSPHONIO)ETHYL CHLOROis also used in research applications, such as the study of protein-protein interactions, enzyme mechanisms, and the development of novel bioactive peptides. The protection of amino and hydroxyl groups allows researchers to investigate the structure-function relationships of these biomolecules and design new peptides with specific biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 61083-59-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,0,8 and 3 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 61083-59:
(7*6)+(6*1)+(5*0)+(4*8)+(3*3)+(2*5)+(1*9)=108
108 % 10 = 8
So 61083-59-8 is a valid CAS Registry Number.
InChI:InChI=1/C21H19ClO2P.ClH/c22-21(23)24-16-17-25(18-10-4-1-5-11-18,19-12-6-2-7-13-19)20-14-8-3-9-15-20;/h1-15H,16-17H2;1H/q+1;/p-1
