61101-89-1

Basic information

• Product Name: 6-Chloro-1,3-dihydroxy-9H-xanthen-9-one
• Synonyms: 6-Chloro-1,3-dihydroxy-9H-xanthen-9-one
• CAS NO: 61101-89-1
• Molecular Formula: C13H7ClO4
• Molecular Weight: 262.64528
• Mol File: 61101-89-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-Chloro-1,3-dihydroxy-9H-xanthen-9-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Chloro-1,3-dihydroxy-9H-xanthen-9-one(61101-89-1)
• EPA Substance Registry System: 6-Chloro-1,3-dihydroxy-9H-xanthen-9-one(61101-89-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 61101-89-1(Hazardous Substances Data)

Upstream product

• 108-73-6 3,5-dihydroxyphenol 
• 5106-98-9 4-chlorosalicylic acid 
• 100334-99-4 2,4-Dichloro-benzoic acid 4-(2,4-dichloro-benzoyl)-3,5-dihydroxy-phenyl ester 
• 10586-12-6 phloroglucinol tris(trimethylsilyl) ether 
• 89-75-8 2,4-dichlorobenzoyl chloride 

Relevant articles and documents

Synthesis and antitumor, antityrosinase, and antioxidant activities of xanthone

Ten substituted 1,3-dihydroxyxanthones were synthesized in one step. The yields ranged from 40 to 76%. Compounds 8–10 were first reported. Next, the compounds’ in vitro anti-proliferative activities against nine human cancer cell lines, antityrosinase, and antioxidant activities were evaluated. Compounds 1, 4, 6–7, and 9–10 exhibited enhanced cytotoxicity against certain cancer cells. Compounds 2, 8, 9, and 10 inhibited tyrosinase activity to a certain extent. In addition, compound 4 exhibited the best antioxidant activity, which was consistent with theoretical calculations. These results demonstrated that compounds 1–2, 4, and 6–10 were promising leads for further investigation.

Thermorubin II: 1,3-dihydroxy-9H-xanthones and 1,3-dihydroxy- 9H-xanthenes. New methods of synthesis

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