612058-40-9

Basic information

• Product Name: Phosphinous acid, diphenyl-, 1-methylcyclopentyl ester
• CAS NO: 612058-40-9
• Molecular Formula: C18H21OP
• Molecular Weight: 284.338
• Mol File: 612058-40-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Phosphinous acid, diphenyl-, 1-methylcyclopentyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphinous acid, diphenyl-, 1-methylcyclopentyl ester(612058-40-9)
• EPA Substance Registry System: Phosphinous acid, diphenyl-, 1-methylcyclopentyl ester(612058-40-9)

Safety Data

• Hazardous Substances Data: 612058-40-9(Hazardous Substances Data)

Upstream product

• 1462-03-9 1-methylcyclopentanol 
• 1079-66-9 chloro-diphenylphosphine 

Downstream Products

• 88722-95-6 1-methylcyclopentanol benzoate 

Relevant articles and documents

A convenient method for the synthesis of dialkyl ethers by alkylation of alcohols using phosphinimidates in the presence of a catalytic amount of trimethylsilyl triflate

An alkylation reaction of alcohols with alkyl N-(methylsulfonyl) diphenylphosphinimidates proceeded smoothly in the presence of a catalytic amount of trimethylsilyl triflate (Me3SiOTf) in DME at room temperature and the corresponding ethers were afforded in good to high yields. An alkyl N-(methylsulfonyl)diphenylphosphinimidate can be prepared easily from an alkyl diphenylphosphinite and methanesulfonyl azide, and is isolated without tedious operation. Moreover, it is easy to handle and can be stored for several months at room temperature because of its air- and moisture-resistant character. Also, one-pot tertiary alkylations of alcohols by using t-alkyl diphenylphosphinites and diphenoxyphosphoryl azide proceeded efficiently in the presence of a catalytic amount of Me3SiOTf in cyclohexane/CH 2Cl2 at 0°C or -10°C, and gave the corresponding tertiary alkyl ethers in good yields. By following these methods, various ethers having alkali-sensitive functional groups can be prepared easily.

Preparation of tert-Alkyl aryl sulfides from tert-alcohols via quinone-mediated oxidation-reduction condensation between tert-Alkyl diphenylphosphinites and 2-sulfanyl-1,3-benzothiazole

A convenient two-step procedure for the construction of sulfur-containing quaternary centers from tert-alcohols involving chiral ones is established. tert-Alkyl diphenylphosphinites 1 were easily prepared in excellent yields from tert-alcohols and ClPPhs

Preparation of various carboxylic acid esters from bulky alcohols and carboxylic acids by a new type oxidation-reduction condensation using 2,6-dimethyl-1,4-benzoquinone

A new-type oxidation-reduction condensation by using 2,6-dimethyl-1,4-benzoquinone (DMBQ), carboxylic acids and in situ formed alkoxydiphenylphosphines (1) including the bulky alkoxy group-substituted ones proceeded smoothly to afford the corresponding carboxylic acid esters in good to high yields. Alkoxydiphenylphosphines were formed in situ by treating either N,N-dimethylaminodiphenylphosphine (Ph2PNMe2) with primary or secondary alcohols or chlorodiphenylphosphine with the lithium salts of primary, secondary and tertiary alcohols.