61227-51-8

Basic information

• Product Name: 3-(3-METHOXY-PHENYL)-2-METHYL-PROPIONIC ACID
• Synonyms: 3-(3-METHOXY-PHENYL)-2-METHYL-PROPIONIC ACID;3-(3-Methoxyphenyl)-2-Methylpropanoic acid
• CAS NO: 61227-51-8
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.22706
• Mol File: 61227-51-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(3-METHOXY-PHENYL)-2-METHYL-PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-METHOXY-PHENYL)-2-METHYL-PROPIONIC ACID(61227-51-8)
• EPA Substance Registry System: 3-(3-METHOXY-PHENYL)-2-METHYL-PROPIONIC ACID(61227-51-8)

Safety Data

• Hazardous Substances Data: 61227-51-8(Hazardous Substances Data)

Usage

Description

3-(3-METHOXY-PHENYL)-2-METHYL-PROPIONIC ACID, also known as Mepirapim, is a chemical compound with the molecular formula C11H14O3. It is a white crystalline powder with a molecular weight of 194.23 g/mol. Mepirapim is a non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting the production of prostaglandins, which are responsible for causing pain and inflammation in the body.

Uses

Used in Pharmaceutical Industry:
3-(3-METHOXY-PHENYL)-2-METHYL-PROPIONIC ACID is used as a non-steroidal anti-inflammatory drug (NSAID) for its ability to relieve pain, reduce inflammation, and lower fever. It is commonly prescribed for conditions such as arthritis, menstrual cramps, and muscle aches.
However, it is important to note that Mepirapim may have side effects such as stomach ulcers, bleeding, and kidney problems, and should be used with caution.

Upstream product

• 66735-17-9 3-(3-methoxyphenyl)-2-methylacrylic acid 
• 591-31-1 3-methoxy-benzaldehyde 
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• 79-10-7 acrylic acid 
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Downstream Products

• 310873-75-7 3-(3-methoxy-phenyl)-2-methyl-propionic acid amide 
• 177362-83-3 2-(3(Z)-benzylidene-7-hydroxy-2-methyl-3H-inden-1-yl)acetamide 
• 1027905-12-9 {3-Carbamoylmethyl-2-methyl-1-[1-phenyl-meth-(E)-ylidene]-1H-inden-4-yloxy}-acetic acid ethyl ester 
• 177362-73-1 2-[3(Z)-benzilidene-7-methoxy-2-methyl-3H-inden-1-yl]-acetamide 
• 177362-64-0 ((3Z)-benzylidene-7-methoxy-2-methyl-3H-inden-1-yl)acetic acid 
• 1075-61-2 Desoxy metaraminol 
• 17862-85-0 3-methoxyamphetamine 

Relevant articles and documents

Carbonylative Transformation of Allylarenes with CO Surrogates: Tunable Synthesis of 4-Arylbutanoic Acids, 2-Arylbutanoic Acids, and 4-Arylbutanals

In this Communication, procedures for the selective synthesis of 4-arylbutanoic acids, 2-arylbutanoic acids, and 4-arylbutanals from the same allylbenzenes have been developed. With formic acid or TFBen as the CO surrogate, reactions proceed selectively and effectively under carbon monoxide gas-free conditions.

Potent inhibitors of secretory phospholipase A2: Synthesis and inhibitory activities of indolizine and indene derivatives

Phospholipase A2 is an enzyme which hydrolyzes the sn-2 position of certain cellular phospholipids. The liberated lysophospholipid and arachidonic acid are precursors in the biosynthesis of various biologically active products. As human nonpancreatic sPLA2 is present in high levels in the blood of patients in several pathological conditions, the potent sPLA2 inhibitors have been suggested to be useful drugs. Here we describe the synthesis, structure-activity relationship, and inhibitory activities of indolizine and indene derivatives. 1-(Carbamoylmethyl)indolizine derivatives and 1-oxamoylindolizine derivatives exhibited very potent inhibitory activity. The former was unstable to air oxidation, but the latter exhibited an improvement both in stability and in potency. Some compounds approached the stoichiometric limit of the chromogenic assay.