61252-00-4

Basic information

• Product Name: Benzenepropanoic acid, 4-aMino-b-oxo-, ethyl ester
• Synonyms: Benzenepropanoic acid, 4-aMino-b-oxo-, ethyl ester;ethyl 3-(4-aMinophenyl)-3-oxopropanoate
• CAS NO: 61252-00-4
• Molecular Formula: C₁₁H₁₃NO₃
• Molecular Weight: 207.22582
• Mol File: 61252-00-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 357.7°Cat760mmHg
• Flash Point: 175.3°C
• Appearance: /
• Density: 1.175g/cm³
• Vapor Pressure: 2.67E-05mmHg at 25°C
• Refractive Index: 1.55
• CAS DataBase Reference: Benzenepropanoic acid, 4-aMino-b-oxo-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, 4-aMino-b-oxo-, ethyl ester(61252-00-4)
• EPA Substance Registry System: Benzenepropanoic acid, 4-aMino-b-oxo-, ethyl ester(61252-00-4)

Safety Data

• Hazardous Substances Data: 61252-00-4(Hazardous Substances Data)

Usage

General Description

Benzenepropanoic acid, 4-amino-b-oxo-, ethyl ester is a chemical compound primarily used as an intermediate in the production of pharmaceuticals and organic compounds. It is an ethyl ester form of 4-amino-3-oxo-benzoic acid, which has potential applications in the synthesis of various drugs and biologically active compounds. Benzenepropanoic acid, 4-aMino-b-oxo-, ethyl ester is also known for its ability to act as an inhibitor of purine nucleoside phosphorylase, an enzyme that plays a crucial role in the proliferation of cancer cells. Its properties and potential pharmaceutical applications make it a valuable chemical compound in the field of medicinal chemistry and drug development.

InChI:InChI=1/C11H13NO3/c1-2-15-11(14)7-10(13)8-3-5-9(12)6-4-8/h3-6H,2,7,12H2,1H3

Upstream product

• 838-57-3 ethyl 4-nitrobenzoylacetate 

Downstream Products

• 110473-55-7 4-<(methanesulfonyl)amino>-β-oxobenzenepropanoic acid ethyl ester 
• 888229-72-9 5-(4-amino-phenyl)-2-methyl-2H-pyrazol-3-ol 
• 401935-11-3 ethyl 3-[4-(4-methylphenylsulfonamido)phenyl]-3-oxopropanoate 
• 91958-11-1 ethyl 3-(4-acetamidophenyl)-3-oxopropanoate 

Relevant articles and documents

BIFUNCTIONAL COMPOUNDS AND USE FOR REDUCING URIC ACID LEVELS

Bifunctional compounds that increase uric acid excretion and reduce uric acid production, and monofunctional compounds that either increase uric acid excretion or reduce uric acid production. Methods of using these compounds for reducing uric acid levels

Synthesis and evaluation of the α-glucosidase inhibitory activity of 3-[4-(phenylsulfonamido)benzoyl]-2H-1-benzopyran-2-one derivatives

In the course of studies directed toward the discovery of novel non-sugar α-glucosidase inhibitors for the treatment of diabetes, a series of 3-[4-(phenylsulfonamido)benzoyl]-2H-1-benzopyran-2-one derivatives was synthesized and evaluated as α-glucosidase inhibitors. Most compounds showed good inhibitory activity with IC50 values ranging from 0.0645?μM to 26.746?μM. 7-Hydroxy-6-methoxy-3-[4-(4-methylphenylsulfonamido)benzoyl]-2H-1-benzopyran-2-one 7u manifested the most potent inhibitory activity with an IC50 value of 0.0645 μM.