612548-45-5 Usage
Description
Perindopril L-Arginine is a complex compound formed by the combination of perindopril, an organoammonium salt with antihypertensive, cardiovascular protective, and antithrombotic properties, and one molar equivalent of L-arginine. This neutral complex has been shown to possess various beneficial effects on the cardiovascular system.
Uses
Used in Pharmaceutical Industry:
Perindopril L-Arginine is used as an active pharmaceutical ingredient for the treatment of hypertension, cardiovascular diseases, and thrombotic conditions. Its antihypertensive properties help in lowering blood pressure, while its cardiovascular protective effects contribute to the prevention of heart-related issues. Additionally, its antithrombotic properties aid in reducing the risk of blood clot formation.
Used in Research and Development:
In the field of research and development, Perindopril L-Arginine is utilized as a compound for studying its potential effects on various physiological processes and exploring its possible applications in the development of new drugs and therapies for cardiovascular and related conditions.
Used in Drug Delivery Systems:
Similar to gallotannin, Perindopril L-Arginine can also be employed in the development of novel drug delivery systems to enhance its bioavailability, delivery, and therapeutic outcomes. By incorporating it into various organic and metallic nanoparticles, researchers can improve the compound's effectiveness in treating the targeted conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 612548-45-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,1,2,5,4 and 8 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 612548-45:
(8*6)+(7*1)+(6*2)+(5*5)+(4*4)+(3*8)+(2*4)+(1*5)=145
145 % 10 = 5
So 612548-45-5 is a valid CAS Registry Number.
612548-45-5Relevant articles and documents
DELTA CRYSTALLINE FORM OF THE ARGININE SALT OF PERINDOPRIL, A PROCESS FOR ITS PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT
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Paragraph 0074; 0075, (2013/07/19)
Delta crystalline form of the compound of formula (I): characterised by its X-ray powder diffraction diagram. Medicinal products containing the same which are useful in the treatment of cardiovascular diseases.
AMORPHOUS FORM OF AN L-ARGININE SALT OF PERINDOPRIL AND PROCESSES FOR PREPARATION THEREOF
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Page/Page column 3-4, (2010/04/23)
In illustrative embodiments, there is provided an amorphous form of L-arginine salt of perindopril which may be particularly suitable for pharmaceutical applications, and processes for preparing said form.
Alpha Crystalline form of the Arginine salt of Perindopril, a Process for its Preparation and Pharmceutical Compositions Containing it.
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Page/Page column 2, (2009/08/18)
α-crystalline form of the compound of formula (I): characterised by its powder X-ray diffraction diagram. Medicinal products containing the same which are useful as inhibitors of angiotensin I converting enzyme.