61302-47-4

Basic information

• Product Name: Cyclopentaneheptanoic acid, 5-(acetyloxy)-2-(hydroxyMethyl)-3-[(tetrahydro-2H-pyran-2-yl)oxy]-, Methyl ester, (1R,2S,3R,5S)-
• Synonyms: Cyclopentaneheptanoic acid, 5-(acetyloxy)-2-(hydroxyMethyl)-3-[(tetrahydro-2H-pyran-2-yl)oxy]-, Methyl ester, (1R,2S,3R,5S)-;Methyl 7-((1R,2S,3R,5S)-5-acetoxy-2-(hydroxymethyl)-3-((tetrahydro-2H-pyran-2-yl)oxy)cyclopentyl);Cyclopentaneheptanoic acid, 5-(acetyloxy)-2-(hydroxyMethyl)-3-[(tetrahydro-2H-pyran-2-yl)oxy]-, Methyl ester,;Methyl 7-((1R,2S,3R,5S)-5-acetoxy-2-(hydroxymethyl)-3-((tetrahydro-2H-pyran-2-yl)oxy)cyclopent;Methyl 7-((1R,2S,3R,5S)-5-acetoxy-2-(hydroxymethyl)-3-((tetrahydro-2H-pyran-2-yl)oxy)cyclopentyl)heptanoate
• CAS NO: 61302-47-4
• Molecular Formula: C21H36O7
• Molecular Weight: 400.50634
• Mol File: 61302-47-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 496.1±45.0 °C(Predicted)
• Appearance: /
• Density: 1.12±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 15.05±0.10(Predicted)
• CAS DataBase Reference: Cyclopentaneheptanoic acid, 5-(acetyloxy)-2-(hydroxyMethyl)-3-[(tetrahydro-2H-pyran-2-yl)oxy]-, Methyl ester, (1R,2S,3R,5S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentaneheptanoic acid, 5-(acetyloxy)-2-(hydroxyMethyl)-3-[(tetrahydro-2H-pyran-2-yl)oxy]-, Methyl ester, (1R,2S,3R,5S)-(61302-47-4)
• EPA Substance Registry System: Cyclopentaneheptanoic acid, 5-(acetyloxy)-2-(hydroxyMethyl)-3-[(tetrahydro-2H-pyran-2-yl)oxy]-, Methyl ester, (1R,2S,3R,5S)-(61302-47-4)

Safety Data

• Hazardous Substances Data: 61302-47-4(Hazardous Substances Data)

Usage

General Description

Cyclopentaneheptanoic acid, 5-(acetyloxy)-2-(hydroxymethyl)-3-[(tetrahydro-2H-pyran-2-yl)oxy]-, methyl ester, (1R,2S,3R,5S)-, is a complex chemical compound with a molecular structure containing cyclopentane, heptanoic acid, acetyloxy, hydroxymethyl, and tetrahydro-2H-pyran-2-yl elements. The methyl ester of this compound has a specific stereochemistry, denoted by the (1R,2S,3R,5S) configuration. Cyclopentaneheptanoic acid, 5-(acetyloxy)-2-(hydroxymethyl)-3-[(tetrahydro-2H-pyran-2-yl)oxy]-, methyl ester, (1R,2S,3R,5S)- may have potential applications in pharmaceuticals, organic synthesis, or as a building block for more complex chemical substances. Its intricate structure and specific stereochemistry make it an interesting and potentially valuable compound for various scientific and industrial purposes.

Upstream product

• 62137-77-3 (Z)-7-[(1R,2R,3R,5S)-5-Acetoxy-2-hydroxymethyl-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-hept-5-enoic acid methyl ester 
• 110-87-2 3,4-dihydro-2H-pyran 
• 31752-99-5 (-)-Corey lactone 5-(4-phenylbenzoate) 
• 65025-95-8 (3aR,4S,5R,6aS)-4-({[dimethyl(2-methyl-2-propanyl)silyl]oxy}methyl)-5-(tetrahydro-2H-pyran-2-yloxy)hexahydro-2H-cyclopenta[b]furan-2-one 
• 58707-50-9 (3aR,4S,5R,6aS)-4-((tert-butyldimethylsilyloxy)methyl)-5-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one 
• 84172-57-6 (Z)-7-[(1R,2S,3R,5S)-2-(t-butyldimethylsilyloxymethyl)-5-hydroxy-3-(2-tetrahydropyranyloxy)cyclopentyl]-5-heptenoic acid 
• 65025-96-9 methyl (5Z)-7-[(1R,2S,3R,5S)-2-({[dimethyl(2-methyl-2-propanyl)silyl]oxy}methyl)-5-hydroxy-3-(tetrahydro-2H-pyran-2-yloxy)cyclopentyl]-5-heptenoate 
• 58707-52-1 (3aR,4S,5R,6aS)-4-({[dimethyl(2-methyl-2-propanyl)silyl]oxy}methyl)-5-(tetrahydro-2H-pyran-2-yloxy)hexahydro-2H-cyclopenta[b]furan-2-ol 
• 165876-61-9 (3aR,4S,5R,6aS)-4-((tert-butyldimethylsilyloxy)methyl)-2-oxo hexahydro-2H-cyclopenta[b]furan-5-yl biphenyl-4-carboxylate 
• 197523-79-8 (Z)-7-[(1R,2S,3R,5S)-5-Acetoxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-hept-5-enoic acid methyl ester 
• 946081-36-3 methyl 7-[(1R,2S,3R,5S)-5-acetoxy-2-(t-butyldimethylsilyloxymethyl)-3-(2-tetrahydropyranyloxy)cyclopentyl]heptanate 
• 17814-85-6 (4-carboxybutyl)triphenylphosphonium bromide 
• 108-24-7 acetic anhydride 
• 74-88-4 methyl iodide 

Downstream Products

• 58682-80-7 misoprostol 
• 1416956-68-7 benzyl 7-[(1R,2R,3R,5S)-2-((6S)-4,4-difluoro-3-hydroxy-6-methyloctyl)-5-hydroxy-3-(tetrahydro-2H-pyran-2-yloxy)cyclopentyl]heptanoate 

Relevant articles and documents

NOVEL PROSTAGLANDIN DERIVATIVE

The present invention relates to a novel prostaglandin derivative having an alkynyl group on ω-chain, particularly, a novel prostaglandin derivative having a double bond at the 2-position and an alkynyl group on the ω-chain and a medicament containing the compound as an active ingredient. According to the present invention, a compound represented by the formula (1) or a pharmaceutically acceptable salt thereof; wherein each symbol is as defined in the present specification, or a cyclodextrin clathrate compound thereof, and a medicament containing the compound as an active ingredient, particularly, a medicament for the prophylaxis or treatment of a blood flow disorder associated with spinal canal stenosis or chronic arterial occlusion, can be provided.

Prostanoids: Synthesis of enantiomers of 15-deoxy-16-hydroxy-16-methylprostaglandin E1

Four optically pure isomers of methyl 11,16-dihydroxy-16-methyl-9-oxoprost-13-enoate (1a-1d) were synthesized using an approach reverse to the classical Corey procedure, the key intermediates being the easily accessible (-)- and (+)-enantiomers of the Corey lactone, 2a and 2b.

Heterocyclic 15-substituted-ω-pentanorprostoglandins

The 15-substituted-ω-pentanorprostaglandins and various intermediates employed in their preparation. The novel prostaglandins of this invention have been found to have activity profiles comparable to the parent prostaglandins, but exhibit a greater tissue specificity of action.