61310-37-0

Basic information

• Product Name: 2-(Pyridin-2-yl)pyriMidin-4-aMine
• Synonyms: 2-(Pyridin-2-yl)pyriMidin-4-aMine
• CAS NO: 61310-37-0
• Molecular Formula: C₉H₈N₄
• Molecular Weight: 172.18662
• Mol File: 61310-37-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 2-(Pyridin-2-yl)pyriMidin-4-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Pyridin-2-yl)pyriMidin-4-aMine(61310-37-0)
• EPA Substance Registry System: 2-(Pyridin-2-yl)pyriMidin-4-aMine(61310-37-0)

Safety Data

• Hazardous Substances Data: 61310-37-0(Hazardous Substances Data)

Usage

General Description

2-(Pyridin-2-yl)pyrimidin-4-amine is a chemical compound with the molecular formula C11H8N4. It is a heterocyclic compound consisting of a pyrimidine ring attached to a pyridine ring at the 2 position. 2-(Pyridin-2-yl)pyriMidin-4-aMine has potential applications in medicinal chemistry, as it is a key structural motif in various pharmaceuticals and biologically active molecules. It may also have relevance in the study of nucleic acids and their interactions with other molecules. Additionally, 2-(Pyridin-2-yl)pyrimidin-4-amine could serve as a building block for the synthesis of various organic compounds with diverse properties and potential applications in drug discovery and materials science.

Upstream product

• 60838-50-8 3-methoxy-2-propenenitrile 
• 51285-26-8 pyridine-2-carboxamidine hydrochloride 

Relevant articles and documents

COMPOUNDS THAT INTERACT WITH THE RAS SUPERFAMILY FOR THE TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES, AND FIBROTIC DISEASE

Provided herein are methods and compositions for treating cancers, inflammatory diseases, rasopathies, and fibrotic disease involving aberrant Ras superfamily signaling through the binding of compounds to the GTP binding domain of Ras superfamily proteins including, in certain cases, K-Ras and mutants thereof, and a novel method for assaying such compositions.

N-(2-(pyridinyl)-4-pyrimidinyl)-aminomethylenemalonates and analogs

Compounds useful as anti-allergic agents are 2-Q-4-[XZC=C(R)NH]-5-R1 -6-R2 -pyrimidines (I), where Q is 4- or 3- or 2-pyridinyl or 4- or 3- or 2-pyridinyl having one or two lower-alkyl substituents or N-oxide thereof, R is hydrogen or lower-alkyl, R1 is hydrogen, lower-alkyl or cyano, R2 is hydrogen, lower-alkyl, hydroxy or halo, X and Z are the same or different and are each selected from lower-carbalkoxy, lower-alkanoyl, carbamyl and cyano, or STR1 where R3 and R4 are each lower-alkyl, or X is hydrogen, are prepared by reacting 4-amino-2-Q-5-R1 -6-R2 -pyrimidine (II where Q' is amino) with R'O-C-(R)=CXZ (III). Preparations of II are given. Also shown as intermediates and/or anti-allergic agents are 4-(AcNH)-2-Q-5-R1 -6-R2 -pyrimidines (IV) and 4-(R5 R6 N)-2-Q-5-R1 -6-R2 -pyrimidines (V) where Ac is lower-alkanoyl or lower-carbalkoxy, R5 is hydrogen, lower-alkyl or lower-hydroxyalkyl, and R6 is lower-alkyl or lower-hydroxyalkyl.