61312-59-2

Basic information

• Product Name: Isobutyl 2-(2-Nitro-Benzylidene)Acetoacetate
• Synonyms: Isobutyl 2-(2-Nitro-Benzylidene)Acetoacetate;2-[(2-Nitrophenyl)methylene]-3-oxobutanoic acid 2-methylpropyl ester
• CAS NO: 61312-59-2
• Molecular Formula: C₁₅H₁₇NO₅
• Molecular Weight: 291.29918
• Mol File: 61312-59-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: 68-69℃
• Boiling Point: 424℃
• Flash Point: 172℃
• Appearance: /
• Density: 1.203
• Vapor Pressure: 2.1E-07mmHg at 25°C
• Refractive Index: 1.558
• Storage Temp.: Amber Vial, -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: Isobutyl 2-(2-Nitro-Benzylidene)Acetoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: Isobutyl 2-(2-Nitro-Benzylidene)Acetoacetate(61312-59-2)
• EPA Substance Registry System: Isobutyl 2-(2-Nitro-Benzylidene)Acetoacetate(61312-59-2)

Safety Data

• Hazardous Substances Data: 61312-59-2(Hazardous Substances Data)

Usage

Uses

Isobutyl 2-(2-Nitrobenzylidene)acetoacetate (cas# 61312-59-2) is a compound useful in organic synthesis.

InChI:InChI=1/C15H17NO5/c1-10(2)9-21-15(18)13(11(3)17)8-12-6-4-5-7-14(12)16(19)20/h4-8,10H,9H2,1-3H3

Upstream product

• 7779-75-1 isobutyl acetoacetate 
• 552-89-6 2-nitro-benzaldehyde 

Downstream Products

• 63675-72-9 nisoldipine 
• 113607-32-2 1,4-Dihydro-2,6-dimethyl-3-isobutoxycarbonyl-4-(2-nitrophenyl)-5-(2-phthalimidoethoxy)carbonyl-pyridine 

Relevant articles and documents

An efficient and recyclable 3D printed α-Al2O3 catalyst for the multicomponent assembly of bioactive heterocycles

A catalytic methodology is reported that enables the efficient, operationally simple and environmentally friendly synthesis of diverse 1,4-dihydropyridines and 3,4-dihydropyrimidin-2(1H)-ones, including some relevant drugs and pharmacologically active derivatives. This strategy is based on the use of a 3D printed Al2O3 woodpile material that was sintered to generate a rigid structure with controlled porosity and noteworthy catalytic performance. The 3D printed Al2O3 catalyst exhibits remarkable efficacy as a Lewis acid in Biginelli and Hantzsch reactions and it can be recovered and reused ten times without any decrease in the activity. Remarkable E factors, excellent recyclability and scalability, broad substrate scope, short reaction times, excellent yields, solvent-free conditions and easy isolation procedures are key features of this methodology.