61327-27-3Relevant articles and documents
Copper-Catalyzed (4+1) Cascade Annulation of Terminal Alkynes with 2-(Tosylmethyl)anilines: Synthesis of 2,3-Disubstituted Indoles
Yan, Xu,Liu, Chun-Fang,An, Xian-Tao,Ge, Xiao-Min,Zhang, Qing,Pang, Lin-Han,Bao, Xu,Fan, Chun-An
, p. 8905 - 8909 (2021/11/24)
A novel strategy based on Cu-catalyzed (4+1) cascade annulation of terminal alkynes as one-carbon synthons with 2-(tosylmethyl)anilines has been developed for the expeditious synthesis of 2,3-disubstituted indoles, in which in situ generations of aza-o-quinone methides and alkynyl-copper(I) species are involved. This annulation provides an effective method for the assembly of synthetically and structurally interesting 2,3-disubstituted indoles.
An efficient iron-promoted synthesis of 6H-indolo[2,3- b] quinolines and neocryptolepine derivatives
Yan, Zicong,Wan, Changfeng,Wan, Jianyong,Wang, Zhiyong
supporting information, p. 4405 - 4408 (2016/06/06)
A facile and practical method for the preparation of 6H-indolo[2,3-b]quinolines and neocryptolepines was developed under the promotion of the easily available ferric trichloride, affording the desired products with moderate to good yields.
A SYNTHETIC EQUIVALENT FOR ORTHO-LITHIO-N-METHYLANILINE
Sisko, Joseph,Weinreb, Steven M.
, p. 1035 - 1042 (2007/10/02)
o-Bromo-N-methyl-N-n-propoxyaniline undergoes halogen-metal exchange with butyllithium and the resulting lithio species reacts cleanly with a variety of electrophiles.The N-O bond of these products can be reduced with Raney nickel to afford ortho-substituted-N-methylanilines.
