61394-92-1 Usage
Description
2,3-dihydro-2,3-dioxo-1H-Indole-5-carbonitrile, also known as isatin-3-cyanohydrin, is a chemical compound that features an indole ring with a dioxo functionality and a cyano group at the 5-position. It is a derivative of isatin, a naturally occurring compound found in various plants. Isatin-3-cyanohydrin is recognized for its unique structural features and reactivity, making it a valuable building block in the synthesis of a wide range of chemical products.
Uses
Used in Pharmaceutical Synthesis:
Isatin-3-cyanohydrin is utilized as a key intermediate in the pharmaceutical industry for the preparation of various drugs. Its unique structure and reactivity allow for the development of new pharmaceutical compounds with potential therapeutic benefits.
Used in Agrochemical Production:
In the agrochemical sector, isatin-3-cyanohydrin serves as an important intermediate for the synthesis of agrochemicals. Its application contributes to the development of new products designed to protect crops and enhance agricultural productivity.
Used in Dye Manufacturing:
Isatin-3-cyanohydrin is also employed in the dye industry as a crucial intermediate for the production of various dyes. Its chemical properties enable the creation of dyes with specific characteristics, catering to different industrial needs.
Used in Biological Research:
Isatin-3-cyanohydrin has been studied for its potential biological activities, such as anticancer, antiviral, and antibacterial properties. This research is valuable for exploring new avenues in medicine and healthcare, potentially leading to the discovery of novel treatments and therapies.
Used in Organic Synthesis:
As a versatile building block, isatin-3-cyanohydrin is widely used in organic synthesis for the preparation of diverse chemical products. Its unique structural features and reactivity make it an essential component in the synthesis of complex organic molecules for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 61394-92-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,3,9 and 4 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 61394-92:
(7*6)+(6*1)+(5*3)+(4*9)+(3*4)+(2*9)+(1*2)=131
131 % 10 = 1
So 61394-92-1 is a valid CAS Registry Number.
61394-92-1Relevant articles and documents
Facile synthesis of isatins by direct oxidation of indoles and 3-iodoindoles using NIS/IBX
Chandra, Ajeet,Yadav, Navin R.,Moorthy, Jarugu Narasimha
supporting information, p. 2169 - 2174 (2019/03/04)
A facile one-pot access to a broad range of isatins by direct oxidation of indoles using NIS/IBX reagent in DMSO at 25 °C in very good isolated yields is reported. It is shown by mechanistic investigations that a number of substituted indoles react rapidly with NIS in DMSO to produce intermediary 3-iodoindoles, which undergo oxidation subsequently to isatins with IBX.
An efficient method based on indoles for the synthesis of isatins by taking advantage of I2O5 as oxidant
Wang, Ci-Ping,Jiang, Guo-Fang
supporting information, p. 1747 - 1750 (2017/04/13)
An efficient method to synthesize isatins based on indoles by using inorganic hypervalent I2O5 has been explored in good yields, which successfully realized the transformation from indoles to isatins under metal-free, mild condition
Indium(III) chloride/2-iodoxybenzoic acid: A novel reagent system for the conversion of indoles into isatins
Yadav,Subba Reddy,Reddy, Ch. Suresh,Krishna
, p. 693 - 696 (2007/12/29)
Indoles and azaindoles undergo smooth oxidation with 2-iodoxybenzoic acid (IBX) in the presence of indium(III) chloride at 80°C to afford the corresponding isatins in excellent yields. This method is very useful for the direct preparation of isatins from indoles. The reaction proceeds smoothly in aqueous media and the products are obtained in excellent yields. Georg Thieme Verlag Stuttgart.
