61404-52-2 Usage
General Description
2-oxo-3-(3,4,5-trimethoxyphenyl)propanoic acid is a chemical compound with the molecular formula C12H14O7. It is a derivative of the amino acid phenylalanine and is often referred to as homoveratric acid. 2-oxo-3-(3,4,5-trimethoxyphenyl)propanoic acid has been studied for its potential pharmacological properties, including anti-inflammatory and antioxidant effects. It is also used in the synthesis of various pharmaceuticals and as a building block for the production of other organic compounds. Its chemical structure contains a phenyl ring with three methoxy groups, as well as a ketone and carboxylic acid functional groups, giving it potential for various chemical interactions and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 61404-52-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,4,0 and 4 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 61404-52:
(7*6)+(6*1)+(5*4)+(4*0)+(3*4)+(2*5)+(1*2)=92
92 % 10 = 2
So 61404-52-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H14O6/c1-16-9-5-7(4-8(13)12(14)15)6-10(17-2)11(9)18-3/h5-6H,4H2,1-3H3,(H,14,15)
61404-52-2Relevant articles and documents
Potent, selective tetrahydro-β-carboline antagonists of the serotonin 2B (5HT(2B)) contractile receptor in the rat stomach fundus
Audia, James E.,Evrard, Deborah A.,Murdoch, Gwyn R.,Droste, James J.,Nissen, Jeffrey S.,Schenck, Kathy W.,Fludzinski, Pawel,Lucaites, Virginia L.,Nelson, David L.,Cohen, Marlene L.
, p. 2773 - 2780 (2007/10/03)
A series of potent, selective 5HT(2B) receptor antagonists has been identified based upon yohimbine, with SAR studies resulting in a 1000-fold increase in 5HT(2B) receptor affinity relative to the starting structure (- log K(B)s > 10.0 have been obtained). These high-affinity tetrahydro-β- carboline antagonists are able to discriminate among the 5HT2 family of serotonin receptors, with members of the series showing selectivities of more than 100-fold versus both the 5HT(2A) and 5HT(2C) receptors based upon radioligand binding and functional assays. As the first compounds reported with such selectivity and enhanced receptor affinity, these tetrahydro-β- carboline antagonists are useful tools for elucidating the role of serotonin acting at the 5HT(2B) receptor in normal and disease physiology.