61423-02-7

Basic information

• Product Name: ethyl 1,1-dimethyl-3-phenylpropargyl acetate
• Synonyms: ethyl 1,1-dimethyl-3-phenylpropargyl acetate
• CAS NO: 61423-02-7
• Molecular Weight: 202.253
• Mol File: 61423-02-7.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: ethyl 1,1-dimethyl-3-phenylpropargyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1,1-dimethyl-3-phenylpropargyl acetate(61423-02-7)
• EPA Substance Registry System: ethyl 1,1-dimethyl-3-phenylpropargyl acetate(61423-02-7)

Safety Data

• Hazardous Substances Data: 61423-02-7(Hazardous Substances Data)

Upstream product

• 1719-19-3 2-Methyl-4-phenyl-3-butyn-2-ol 
• 75-36-5 acetyl chloride 
• 536-74-3 phenylacetylene 
• 1612-03-9 3-methyl-1-phenyl-but-1-yne 
• 67-64-1 acetone 
• 108-24-7 acetic anhydride 
• 463-51-4 Ketene 

Downstream Products

• 143212-41-3 2,2-dimethyl-1,4-diphenylbut-3-yn-1-ol 
• 1402591-51-8 (Z)-3-benzoyl-5-benzylidene-4,4-dimethyldihydrofuran-2(3H)-one 
• 1402591-68-7 6,6-dimethyl-8-phenyl-7-octyne-2-one 
• 1402591-76-7 (Z)-5-benzylidene-4,4-dimethyl-3-(4-methylbenzoyl)dihydrofuran-2(3H)-one 
• 1402591-60-9 3,3-dimethyl-5-phenyl-1-(4-methylphenyl)-4-pentyne-1-one 
• 1402591-86-9 (Z)-5-benzylidene-4,4-dimethyl-3-(3-phenylpropionyl)-dihydrofuran-2(3H)-one 
• 1402591-69-8 5,5-dimethyl-1,7-diphenyl-hept-6-yne-3-one 
• 1402591-62-1 3,3-dimethyl-1-(4-methoxyphenyl)-5-phenyl-4-pentyne-1-one 
• 1402591-78-9 (Z)-5-benzylidene-4,4-dimethyl-3-(4-methoxbenzoyl)dihydrofuran-2(3H)-one 
• 1402591-65-4 3,3-dimethyl-1-(1-naphthyl)-5-phenyl-4-pentyne-1-one 
• 1402591-81-4 (Z)-5-benzylidene-4,4-dimethyl-3-(1-naphthoyl)-dihydrofuran-2(3H)-one 
• 1402591-63-2 3,3-dimethyl-1-(3-methoxyphenyl)-5-phenyl-4-pentyne-1-one 
• 1402591-79-0 (Z)-5-benzylidene-4,4-dimethyl-3-(3-methoxybenzoyl)dihydrofuran-2(3H)-one 
• 1402591-64-3 3,3-dimethyl-1-(2-methoxyphenyl)-5-phenyl-4-pentyne-1-one 

Relevant articles and documents

Synthesis of Multisubstituted Allenes via Palladium-Catalyzed Cross-Coupling Reaction of Propargyl Acetates with an Organoaluminum Reagent

We describe a convenient method for the synthesis of multisubstituted allenes from cross-coupling of propargyl acetates with -organoaluminum reagent: The reaction of propargyl acetates with 1.2 equivalents of organoaluminum reagent mediated by Pd(PPh3)2Cl2 (1 mol%)/Ph3P (2 mol%) and K2CO3 in THF may produce tri- or tetrasubstituted allenes in good to excellent yields (83-94%) and high regio-selectivities (up to 99%) at 60 °C in 3-4 hours.

Synthesis and evaluation of 1,1,7,7-tetramethyl-9-azajulolidine (TMAJ) as a highly active derivative of N,N-dimethylaminopyridine

1,1,7,7-Tetramethyl-9-azajulolidine (TMAJ), which theoretical studies have suggested as a highly active DMAP analog, was synthesized for the first time. The catalytic activity of TMAJ was confirmed by the acetylation reactions of various tert-alcohols. TMAJ showed much higher catalytic activity than DMAP and one of the highest activity levels among the conventional DMAP analogs. These experimental results were in good agreement with the previous theoretical studies.

Palladium-catalyzed, ligand-free SN2’ substitution reactions of organoaluminum with propargyl acetates for the synthesis of multi-substituted allenes

We describe a convenient method for the synthesis of multi-substituted allenes from SN2′ substitution reactions organoaluminum with propargyl acetates: The SN2′ substitution reaction of organoaluminum (0.4 mmol) with propargyl acetat