61424-76-8

Basic information

• Product Name: 2-AMINO-3-FORMYLCHROMONE
• Synonyms: 2-amino-4-oxo-chromene-3-carbaldehyde;2-amino-4-oxochromene-3-carbaldehyde;2-AMINO-3-FORMYLCHROMONE;2-AMINO-4-OXO-4 H-1-BENZOPYRAN-3-CARBOXALDEHYDE;2-AMINO-4-OXO-4H-CHROMENE-3-CARBALDEHYDE;2-Aminochromone-3-carboxaldehyde;2-amino-4-keto-chromene-3-carbaldehyde;2-amino-4-oxo-3-chromenecarboxaldehyde
• CAS NO: 61424-76-8
• Molecular Formula: C₁₀H₇NO₃
• Molecular Weight: 189.17
• Product Categories: Chromones;Heterocyclic Compounds
• Mol File: 61424-76-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 249 °C (dec.)(lit.)
• Boiling Point: 401.2°C at 760 mmHg
• Flash Point: 241°C
• Appearance: /
• Density: 1.486g/cm³
• Vapor Pressure: 1.2E-06mmHg at 25°C
• Refractive Index: 1.713
• PKA: 1.31±0.20(Predicted)
• CAS DataBase Reference: 2-AMINO-3-FORMYLCHROMONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-3-FORMYLCHROMONE(61424-76-8)
• EPA Substance Registry System: 2-AMINO-3-FORMYLCHROMONE(61424-76-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 61424-76-8(Hazardous Substances Data)

Usage

Uses

2-Amino-3-formylchromone may be used in the preparation of the following:chiral Schiff base ligands (R)/(S)-2-amino-3-(((1-hydroxypropan-2-yl)imino)methyl)-4H-chromen-4-onehydrazone derivatives, required for the synthesis of heterocyclic Schiff′s bases having antimicrobial activityN-{4-[(6-chloro-4-oxo-4H-chromen-3-ylmethylene)amino]phenyl}-3,5-dimethyl-benzofuran-2-carboxamideN-{4-[(6-chloro-4-oxo-4H-chromen-3-ylmethylene)amino]phenyl}-1,4-dihydro-chromono [2,3-b]pyrrole-2-carboxamide6-chloro-3-{[4-(2-thioxo-3,6-dihydro-2H-1,3,4-thiadiazin-5-ylamino)phenylimino] methyl}- 4-oxo-4H -chromene3--(2-amino--4--oxo--4H--chromen--3--yl)methylidene)--6-- ethyl--2H--pyrano[3,2--c]quinolone--2,4,5(3H,6H)-trione

General Description

2-Amino-3-formylchromone (2-Amino-4-oxo-4H-1-benzopyran-3-carboxaldehyde) is a benzopyran derivative. It is a bicyclic heterocyclic molecule made up of a benzene ring fused to a heterocyclic pyran ring. It undergoes condensation with (R)-2-amino-2-phenylethanol to afford Schiff base ligand, which forms complexes with Cu(NO3)2 and Zn(NO3)2.

InChI:InChI=1/C10H7NO3/c11-10-7(5-12)9(13)6-3-1-2-4-8(6)14-10/h1-5H,11H2

Upstream product

• 50743-17-4 4-oxo-4H-1-benzopyran-3-carbonitrile 
• 107-15-3 ethylenediamine 

Downstream Products

• 61424-77-9 3-phenyl-3H-chromeno[2,3-d]pyrimidine-2,5-dione 
• 61424-81-5 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carbonitrile 
• 38518-76-2 2-amino-4H-1-benzopyran-4-one 
• 1076-38-6 4-hydroxy[1]benzopyran-2-one 
• 73262-21-2 2-(4-oxo-4H-[1]benzopyran-3-yl) [1] benzopyrano[3,2-e]pyrimidin-5(5H)-one 
• 90701-02-3 Bis-<1>benzopyrano<2,3-b:3',2'-e>pyridin-5(5H),7(7H)-dion 
• 869637-43-4 2-(4-chlorophenyl)-5-oxo-5H-chromeno[2,3-b]pyridine-3-carbonitrile 
• 1028435-78-0 C₁₈H₁₁NO₂ 
• 1028435-82-6 C₁₉H₁₃NO₂ 
• 1028435-80-4 C₁₉H₁₃NO₂ 
• 1214887-11-2 4-{[(2-amino-4-oxo-4H-chromen-3-yl)methylene]amino}-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one 
• 1214887-10-1 3-{[(2-acetylphenyl)imino]methyl}-2-amino-4H-chromen-4-one 
• 1214886-97-1 N'-[(2-amino-4-oxo-4H-chromen-3-yl)methylene]benzohydrazide 
• 1301190-16-8 2-amino-3-(2-hydroxyphenyliminomethyl)chromone 

Relevant articles and documents

Heterocyclic Systems. 8. Condensation Reactions of 4-Oxo-4H-benzopyran-3-carbonitrile

Condensation reactions of 4-oxo-4H-benzopyran-3-carbonitriles (1; X=H, CH3, Cl, and Br) with 1,2-diamines, acetylglycine, and themselves have been investigated.The compounds 1 on being refluxed with ethylenediamine in ethanol give initially 1,4-additio