61441-65-4 Usage
Description
[(2S,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methanol, commonly known as clotrimazole, is an antifungal medication with potent fungicidal properties. It is characterized by its ability to inhibit the growth of various fungi, making it a widely used treatment for a range of fungal infections.
Uses
Used in Pharmaceutical Applications:
Clotrimazole is used as an antifungal agent for treating a variety of fungal infections, such as athlete's foot, ringworm, jock itch, and yeast infections. It works by targeting the fungal cell membrane, disrupting its integrity and ultimately inhibiting fungal growth.
Used in Topical Medications:
Clotrimazole is used as an active ingredient in creams, powders, and topical solutions for external use. These formulations are designed to provide targeted relief and treatment for skin infections caused by fungi.
Used in Oral Health:
Clotrimazole is also used in the form of oral lozenges for the treatment of oral thrush, a fungal infection that affects the mouth and throat. Its antifungal properties help to alleviate symptoms and promote healing in the affected areas.
Used in Veterinary Medicine:
In addition to human applications, clotrimazole is also utilized in veterinary medicine to treat fungal infections in animals, showcasing its broad-spectrum antifungal capabilities.
Overall, clotrimazole is a versatile and effective antifungal agent that is well-tolerated by patients, making it a popular choice for treating a wide range of fungal infections across various industries and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 61441-65-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,4,4 and 1 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 61441-65:
(7*6)+(6*1)+(5*4)+(4*4)+(3*1)+(2*6)+(1*5)=104
104 % 10 = 4
So 61441-65-4 is a valid CAS Registry Number.
61441-65-4Relevant articles and documents
Synthesis, antifungal activity and structure-activity relationships of 2-(alkyl or aryl)-2-(alkyl or polyazol-1-ylmethyl)-4-(polyazol-1-ylmethyl)- 1,3-dioxolanes
Baji,Kimny, Tan,Gasquez,Flammang,Compagnon,Delcourt,Mathieu,Viossat,Morgant,Nguyen-Huy
, p. 637 - 650 (2007/10/03)
A series of 2-(alkyl or aryl)-2-(alkyl or polyazol-1-ylmethyl)-4-(polyazol-1-ylmethyl)-1,3-dioxolanes Ia-u was synthesized and tested in vitro against pathogenic fungi in man, animals and plants: Candida albicans, Aspergillus flavus and Fusarium solani. Compounds Iq-t with two polyazol groups have an in vitro activity against these fungi with MIC (minimum inhibitory concentration) value of 5 μg mL-1.
