61442-09-9

Basic information

• Product Name: methyl 3-bromo-2-methylprop-2-enoate
• Synonyms: 2-propenoic acid, 3-bromo-2-methyl-, methyl ester; Methyl 3-bromo-2-methylacrylate
• CAS NO: 61442-09-9
• Molecular Formula: C₅H₇BrO₂
• Molecular Weight: 179.0119
• Mol File: 61442-09-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 172.4°C at 760 mmHg
• Flash Point: 58.1°C
• Density: 1.477g/cm³
• Vapor Pressure: 1.33mmHg at 25°C
• Refractive Index: 1.483
• CAS DataBase Reference: methyl 3-bromo-2-methylprop-2-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-bromo-2-methylprop-2-enoate(61442-09-9)
• EPA Substance Registry System: methyl 3-bromo-2-methylprop-2-enoate(61442-09-9)

Safety Data

• Hazardous Substances Data: 61442-09-9(Hazardous Substances Data)

Upstream product

• 3673-79-8 methyl 2,3-dibromoisobutyrate 
• 120-80-9 benzene-1,2-diol 
• 80-62-6 methacrylic acid methyl ester 

Downstream Products

• 91900-66-2 3--2-methyl-acrylsaeure 
• 118670-63-6 methyl 3-phenoxy-2-(phenoxymethyl)acrylate 
• 118670-69-2 2-Diphenoxymethyl-acrylic acid methyl ester 
• 118670-64-7 (Z)-3-p-Tolyloxy-2-p-tolyloxymethyl-acrylic acid methyl ester 
• 118670-70-5 2-(Bis-p-tolyloxy-methyl)-acrylic acid methyl ester 
• 118670-65-8 (Z)-3-(4-Chloro-phenoxy)-2-(4-chloro-phenoxymethyl)-acrylic acid methyl ester 
• 118670-73-8 2-[Bis-(4-ethyl-phenoxy)-methyl]-acrylic acid methyl ester 
• 118670-71-6 2-[Bis-(4-chloro-phenoxy)-methyl]-acrylic acid methyl ester 
• 118670-72-7 2-[Bis-(2,4-dichloro-phenoxy)-methyl]-acrylic acid methyl ester 
• 118670-66-9 (Z)-3-(2,4-Dichloro-phenoxy)-2-(2,4-dichloro-phenoxymethyl)-acrylic acid methyl ester 
• 118670-68-1 (Z)-3-(Biphenyl-4-yloxy)-2-(biphenyl-4-yloxymethyl)-acrylic acid methyl ester 
• 118670-74-9 2-[Bis-(biphenyl-4-yloxy)-methyl]-acrylic acid methyl ester 
• 84695-29-4 (E)-3-bromo-2-methyl-prop-2-en-1-ol 

Relevant articles and documents

Synthesis of the conjugated tetraene acid side chain of mycolactone e by Suzuki-Miyaura cross-coupling reaction of alkenyl boronates

The conjugated tetraene acid side chain of mycolactone E has been synthesized by the cross-coupling reaction of a trisubstituted triene bromide with a trisubstituted alkenyl boronate catalyzed by Pd(OAc)2-Aphos-Y under mildly basic conditions [K3PO4·3H 2O, H2O, tetrahydrofuran (THF), 35 °C, 18 h]. The conjugated tetraene product was obtained in 85 % yield without geometrical isomer(s) under the catalytic conditions. These results demonstrated that the coupling of alkenyl halides with alkenyl boronates catalyzed by Pd(OAc) 2-Aphos-Y in combination with CuI-catalyzed regio- and stereoselective alkyne borylation offers an efficient synthetic tool for accessing conjugated polyene molecules. Gently united: Conjugate polyenes possessing trisubstituted double bond(s) are synthesized from trisubstituted alkenyl halides and trisubstituted boronates in high yields under the catalysis of the hemilabile P,O ligand Aphos-Y and Pd(OAc)2 in the presence of K3PO4·3H2O (3 equiv.) and H2O (18 equiv.) in tetrahydrofuran (THF) at 35°C. The product is free of geometric isomers. Copyright

Process for preparing beta-L-2'deoxy-thymidine

The present invention relates to a new, essentially four-step process for preparing beta-L-2′-deoxy-thymidine starting from L-arabinose. The process according to the invention is particularly important for mass production of beta-L-2′-deoxy-thymidine.

(2-Alkyl-1,4-benzodioxan-2-yl)carboxylic acids as potential hypolipidemic agents

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