61449-04-5Relevant articles and documents
ISOXAZOLES AS 4b-DIKETONE SYNTHONS-SELECTIVE ANION FORMATION ON 3,5-DIALKYLISOXAZOLES
Brunelle, D. J.
, p. 3699 - 3702 (2007/10/02)
3,5-Dimethylisoxazole can be metalated and alkylated regiospecifically.Alkylation occurs first on the 5-methyl group, and a second alkylation occurs on the 3-methyl group.This method permits specific synthesis of disubstituted isoxazoles, and of the corresponding β-diketones.