61463-59-0

Basic information

• Product Name: Benzoic acid, 2-(2-propenyl)-, methyl ester
• Synonyms: 2-allyl benzoic acid methyl ester;o-Allylmethylbenzoat;methyl 2-allylbenzoate
• CAS NO: 61463-59-0
• Molecular Formula: C11H12O2
• Molecular Weight: 176.215
• Mol File: 61463-59-0.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-(2-propenyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-(2-propenyl)-, methyl ester(61463-59-0)
• EPA Substance Registry System: Benzoic acid, 2-(2-propenyl)-, methyl ester(61463-59-0)

Safety Data

• Hazardous Substances Data: 61463-59-0(Hazardous Substances Data)

Upstream product

• 610-97-9 o-iodo-methyl-benzoic acid 
• 107-05-1 3-chloroprop-1-ene 
• 106-95-6 allyl bromide 
• 88-67-5 2-Iodobenzoic acid 
• 24850-33-7 allyltributylstanane 
• 374538-03-1 2-methoxycarbonylphenylboronic acid 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 591-87-7 Allyl acetate 
• 17763-70-1 methyl 2-(trifluoromethylsulfonyloxy)benzoate 
• 72824-04-5 2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 201230-82-2 carbon monoxide 

Downstream Products

• 62723-81-3 (2-methoxycarbonylphenyl)acetaldehyde 
• 1269142-29-1 tert-butyl 2-(3-allyl-3-(2-allylbenzoyl)ureido)benzylcarbamate 
• 1269142-28-0 N,2-diallylbenzamide 
• 1310538-72-7 2-allyl-N-tosylbenzamide 
• 61436-73-5 2-allylbenzoic acid 
• 1612776-39-2 2-(4-oxobutyl)benzoic acid 
• 1351765-81-5 2-allyl-N-phenylbenzamide 
• 17496-14-9 2,3-dihydro-2-methyl-1H-inden-1-one 
• 39172-65-1 methyl 4-((1-oxo-2,3-dihydro-1H-inden-2-yl)methyl)benzoate 

Relevant articles and documents

MODIFIED PROTEINS AND PROTEIN DEGRADERS

Provided herein are compounds, pharmaceutical compositions, and methods for binding or degrading target proteins. Further provided herein are compounds having a DNA damage-binding protein 1 (DDB1) binding moiety. Some such embodiments include a linker. Some such embodiments include a target protein binding moiety. Further provided herein are ligand-DDB1 complexes. Further provided herein are in vivo modified DDB1 proteins.

Copper-Catalyzed Modular Amino Oxygenation of Alkenes: Access to Diverse 1,2-Amino Oxygen-Containing Skeletons

Copper-catalyzed alkene amino oxygenation reactions using O-acylhydroxylamines have been achieved for a rapid and modular access to diverse 1,2-amino oxygen-containing molecules. This transformation is applicable to the use of alcohols, carbonyls, oximes, and thio-carboxylic acids as nucleophiles on both terminal and internal alkenes. Mild reaction conditions tolerate a wide range of functional groups, including ether, ester, amide, carbamate, and halide. The reaction protocol allows for starting with free amines as the precursor of O-benzoylhydroxylamines to eliminate their isolation and purification, contributing to broader synthetic utilities. Mechanistic investigations reveal the amino oxygenation reactions may involve distinct pathways, depending on different oxygen nucleophiles.

Cyclic Hypervalent Iodine Reagents for Azidation: Safer Reagents and Photoredox-Catalyzed Ring Expansion

Azides are building blocks of increasing importance in synthetic chemistry, chemical biology, and materials science. Azidobenziodoxolone (ABX, Zhdankin reagent) is a valuable azide source, but its safety profile has not been thoroughly established. Herein, we report a safety study of ABX, which shows its hazardous nature. We introduce two derivatives, tBu-ABX and ABZ (azidobenziodazolone), with a better safety profile, and use them in established photoredox- and metal-mediated azidations, and in a new ring-expansion of silylated cyclobutanols to give azidated cyclopentanones.