61532-49-8

Basic information

• Product Name: 4-Piperidinecarboxylic acid, 1-(2-hydroxyethyl)-4-phenyl-, ethyl ester
• CAS NO: 61532-49-8
• Molecular Formula: C16H23NO3
• Molecular Weight: 277.364
• Mol File: 61532-49-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-Piperidinecarboxylic acid, 1-(2-hydroxyethyl)-4-phenyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinecarboxylic acid, 1-(2-hydroxyethyl)-4-phenyl-, ethyl ester(61532-49-8)
• EPA Substance Registry System: 4-Piperidinecarboxylic acid, 1-(2-hydroxyethyl)-4-phenyl-, ethyl ester(61532-49-8)

Safety Data

• Hazardous Substances Data: 61532-49-8(Hazardous Substances Data)

Upstream product

• 75-21-8 oxirane 
• 77-17-8 Normeperidine 
• 108-10-1 4-methyl-2-pentanone 
• 107-07-3 2-chloro-ethanol 

Downstream Products

• 61532-50-1 1-(2-chloro-ethyl)-4-phenyl-piperidine-4-carboxylic acid ethyl ester; hydrochloride 
• 122764-96-9 1-[2-(3-nitro-anilino)-ethyl]-4-phenyl-piperidine-4-carboxylic acid ethyl ester; hydrochloride 
• 122747-57-3 1-[2-(4-nitro-anilino)-ethyl]-4-phenyl-piperidine-4-carboxylic acid ethyl ester; hydrochloride 
• 110664-80-7 1-[2-(4-chloro-anilino)-ethyl]-4-phenyl-piperidine-4-carboxylic acid ethyl ester; dihydrochloride 
• 13830-05-2 1-(2-anilino-ethyl)-4-phenyl-piperidine-4-carboxylic acid ethyl ester 

Relevant articles and documents

1-Triarylalkyl-4-phenyl-4-piperidine carboxylic acids and derivatives

The present invention encompasses compounds of the formula STR1 wherein the Alk is straight or branched chain alkylene containing 2-4 carbon atoms; Ar and Ar' are phenyl, Alkyl substituted phenyl wherein the alkyl contains from 1-4 carbon atoms or halo substituted phenyl; Ar" is phenyl, alkyl substituted phenyl wherein the alkyl contains 1-4 carbon atoms, halo substituted phenyl or pyridyl; X is hydrogen, halogen, trifluoromethyl or alkyl having from 1-4 carbon atoms; R is hydrogen, alkyl having from 1-7 carbon atoms, alkenyl having 3-7 carbon atoms, Ar" as herein before defined, or a cation selected from the group consisting of sodium, potassium, ammonium or calcium/2. Compounds of the present invention are potent antidiarrheal agents with little, if any, central nervous system activity.