61543-56-4

Basic information

• Product Name: BOC-PHE-MET-OH
• Synonyms: BOC-L-PHENYLALANYL-L-METHIONINE;BOC-PHE-MET-OH;Boc-L-Phe-L-Met-OH;(5S,8S)-8-benzyl-12,12-dimethyl-7,10-dioxo-11-oxa-2-thia-6,9-diazatridecane-5-carboxylic acid;REF DUPL: Boc-Phe-Met-OH
• CAS NO: 61543-56-4
• Molecular Formula: C₁₉H₂₈N₂O₅S
• Molecular Weight: 396.5
• Mol File: 61543-56-4.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BOC-PHE-MET-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-PHE-MET-OH(61543-56-4)
• EPA Substance Registry System: BOC-PHE-MET-OH(61543-56-4)

Safety Data

• Hazardous Substances Data: 61543-56-4(Hazardous Substances Data)

Upstream product

• 63-68-3 L-methionine 
• 3674-06-4 Boc-Phe-ONSu 
• 40290-63-9 Methyl ester of N-t-butyloxycarbonyl-L-phenylalanyl-L-methionine 
• 63-68-3 L-methionine 
• 7535-56-0 p-nitrophenylester of N-tert-butoxycarbonylphenylalanine 
• 50903-54-3 N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanine pentafluorophenyl ester 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 59-51-8 DL-methionine 
• 77-92-9 citric acid 

Downstream Products

• 61543-22-4 Boc-Phe-Met-OBzl 
• 96012-51-0 Boc-Phe-Met-NHC₆H₁₃(n) 
• 84969-32-4 Boc-Phe-Met-Gly-Gly-OMe 
• 84969-48-2 6-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-4-methylsulfanyl-butyrylamino]-hexanoic acid methyl ester 
• 126369-85-5 (N-tert-butyloxycarbonyl-L-phenylalanyl-L-methionine)-O-pentachlorophenyl ester 
• 62530-45-4 (S)-2-((S)-2-Amino-3-phenyl-propionylamino)-4-methylsulfanyl-butyric acid; hydrochloride 
• 96012-49-6 Boc-Phe-Met-NHC₂H₅ 
• 96012-50-9 Boc-Phe-Met-NHC₃H₇(iso) 
• 125816-01-5 (S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-4-methylsulfanyl-butyric acid 2-cyano-ethyl ester 
• 84969-41-5 H-Phe-Met-Gly-Gly-OH 
• 84969-43-7 H-Phe-Met(O)-Gly-Gly-OH 
• 84969-33-5 Boc-Phe-Met-Gly-Gly-OH 
• 84969-50-6 6-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-4-methylsulfanyl-butyrylamino]-hexanoic acid 4-nitro-phenyl ester 
• 77052-98-3 6-[(S)-2-((S)-2-Amino-3-phenyl-propionylamino)-4-methylsulfanyl-butyrylamino]-hexanoic acid 

Relevant articles and documents

A one-pot saponification-coupling sequence suitable for C-terminus peptide elongation using lithium carboxylates

An efficient procedure has been developed for the saponification of common peptide esters, followed by straightforward coupling of the lithium carboxylate. Adding some water to the reaction medium gave faster saponification and did not interfere with the coupling reagent. As peptide chemistry constitutes a major application of the amidation reaction, amino acid substrates were chosen for this study, monitoring both yields and epimerization of the peptides obtained. Georg Thieme Verlag Stuttgart New York.

Selective detachment of Boc-protected amino acids and peptides from Merrifield, PAM and Wang resins by trimethyltin hydroxide

We describe the development of a new non-acidolytic and non- nucleophilic method for the selective cleavage by trimethyltin hydroxide of amino acids and dipeptides at benzyl ester links attached to resins commonly used in peptide synthesis.

Design and Synthesis of Enkephalin Analogues: Part II - Synthesis of 2, Met5>-Enkephalin Alkylamides Having Morphinomimetic Activity

Alkylamides of 2, Met5>-enkephalin have been synthesized by two different routes.The first method consists of the sequential peptidation of Phe-Met-ONBzl by 2,4,5-trichlorophenyl esters of Boc-Gly, Boc-D-Ala and Boc-Tyr to get