6158-93-6Relevant articles and documents
Synthesis of deuterated mevalonolactone isotopomers
Dickschat, Jeroen S.,Citron, Christian A.,Brock, Nelson L.,Riclea, Ramona,Kuhz, Henning
experimental part, p. 3339 - 3346 (2011/08/03)
A synthetic route was developed for the preparation of deuterated mevalonolactones. Using low-cost deuterated reagents, this route allows for the independent introduction of deuterium labeling into any carbon position or into any combination of positions. Following this approach, the synthesis of [6,6,6-2H3]mevalonolactone, [4,4,6,6,6-2H 5]mevalonolact-one, [5,5-2H2]mevalonolactone, [5,5,6,6,6-2H5]mevalonolact-one, and [2,2,6,6,6- 2H5]mevalonolactone is described.
A New Flexible Synthesis of (R,S)-Mevalonolactone
Ferraboschi, Patrizia,Canevotti, Renato,Grisenti, Paride,Santaniello, Enzo
, p. 2301 - 2304 (2007/10/02)
By selective ozonolysis of the diene (5), a new synthesis of (R,S)-mevalonolactone (1a) has been developed, which can be adapted to other compounds related to (1a).This has been exemplified by the synthesis of the monodeuteriated triol (4d) and dideuteriated mevalonolactone (1d).