61630-32-8

Basic information

• Product Name: 4-ANDROSTEN-4-OL-3,17-DIONE ACETATE
• Synonyms: 17-dione,4-hydroxy-androst-4-ene-acetate(ester);4-(acetyloxy)-androst-4-ene-17-dione;4-acetoxy-4-androstene-3,17-dione;4-HYDROXY ANDROSTENEDIONE ACETATE;4-ANDROSTEN-4-OL-3,17-DIONE ACETATE;4-ACETOXY-4-ANDROSTENE-3,12-DIONE;4-Androsten-4-oi-3,17-dione acetate;[(8R,9S,10R,13S,14S)-10,13-dimethyl-3,17-dioxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-4-yl] acetate
• CAS NO: 61630-32-8
• Molecular Formula: C21H28O4
• Molecular Weight: 344.44
• Mol File: 61630-32-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 184-185 °C
• Boiling Point: 501.2°C at 760 mmHg
• Flash Point: 219.2°C
• Appearance: /
• Density: 1.18g/cm³
• Vapor Pressure: 3.54E-10mmHg at 25°C
• Refractive Index: 1.548
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-ANDROSTEN-4-OL-3,17-DIONE ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ANDROSTEN-4-OL-3,17-DIONE ACETATE(61630-32-8)
• EPA Substance Registry System: 4-ANDROSTEN-4-OL-3,17-DIONE ACETATE(61630-32-8)

Safety Data

• WGK Germany: 3
• RTECS: BV8153000
• Hazardous Substances Data: 61630-32-8(Hazardous Substances Data)

Usage

General Description

4-Androsten-4-ol-3,17-dione acetate is a chemical compound that is a derivative of the naturally occurring hormone, testosterone. It is a prohormone, meaning that it can be converted by the body into an active hormone, in this case, testosterone. It is commonly used as a supplement in the fitness and bodybuilding industries to increase muscle mass, strength, and athletic performance. 4-Androsten-4-ol-3,17-dione acetate is believed to promote protein synthesis and enhance muscle recovery, making it popular among athletes and bodybuilders looking to improve their physical performance and body composition. However,

InChI:InChI=1/C21H28O4/c1-12(22)25-19-16-5-4-13-14-6-7-18(24)21(14,3)10-8-15(13)20(16,2)11-9-17(19)23/h13-15H,4-11H2,1-3H3/t13-,14-,15-,20+,21-/m0/s1

Upstream product

• 108-24-7 acetic anhydride 
• 566-48-3 4-hydroxyandrost-4-ene-3,17-dione 
• 66880-12-4 5-α-fluoro-4α-hydroxyandrostane-3,17-dione 
• 75-36-5 acetyl chloride 
• 77057-73-9 4,5-epoxyandrostane-3,17-dione 
• 5538-51-2 O-acetylsalicyloyl chloride 

Relevant articles and documents

3,17-Dioxoandrost-4-en-4-yl acetate

The title compound, C21H28O4, has a 4-acet-oxy substituent positioned on the steroid face. The six-membered ring A assumes a conformation inter-mediate between 1,2Β-half chair and 1-sofa. A long Csp 3 - Csp 3 bond is observed in ring B and reproduced in quantum-mechanical ab initio calculations of the isolated mol-ecule using a mol-ecular-orbital Hartree-Fock method. Cohesion of the crystal can be attributed to van der Waals inter-actions and weak C - H...O hydrogen bonds. International Union of Crystallography 2007.

Topical treatment for mastalgia

A composition for medicinal treatment by means of topical administration is described, which contains an aromatase inhibitor, in addition to conventional constituents of topical forms of administration. The active ingredient or the composition containing this active ingredient is especially suitable for the prophylaxis and for the treatment of mastalgia.

The Synthesis of 4-Hydroxyandrost-4-ene-3,17-dione and other Potential Aromatase Inhibitors

We describe novel syntheses of 4-hydroxyandrost-4-ene-3,17-dione (Ia) and related compounds, some containing fluorine.In addition we provide further evidence of the general tendency of 2- and 6-substituted androst-4-ene-3,17-diones to undergo rearrangement reactions, and thus provide new routes to 6-fluoro- and 2,6-difluoro-derivatives.Several of these compounds are potent aromatase inhibitors.