61709-46-4

Basic information

• Product Name: 1,5-Benzodiazocine, 3-chloro-6-(2-fluorophenyl)-1,2,3,4-tetrahydro-1-methyl-
• CAS NO: 61709-46-4
• Molecular Formula: C17H16ClFN2
• Molecular Weight: 302.779
• Mol File: 61709-46-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,5-Benzodiazocine, 3-chloro-6-(2-fluorophenyl)-1,2,3,4-tetrahydro-1-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-Benzodiazocine, 3-chloro-6-(2-fluorophenyl)-1,2,3,4-tetrahydro-1-methyl-(61709-46-4)
• EPA Substance Registry System: 1,5-Benzodiazocine, 3-chloro-6-(2-fluorophenyl)-1,2,3,4-tetrahydro-1-methyl-(61709-46-4)

Safety Data

• Hazardous Substances Data: 61709-46-4(Hazardous Substances Data)

Upstream product

• 59772-70-2 2-fluoro-N-[2-hydroxy-3-(methylphenylamino)propyl]benzamide 

Downstream Products

• 94030-96-3 N-{[5-(2-fluorophenyl)-2,3-dihydro-1-methyl-1H-1,4-benzodiazepin-2-yl]methyl}phthalimide 
• 102428-91-1 1-methyl-2-(3'-trifluoromethylphenyl)aminomethyl-5-(2'-fluorophenyl)-2,3-dihydro-1H-1,4-benzodiazepine 
• 61677-47-2 7-bromo-5-(2-fluoro-phenyl)-2-methoxymethyl-1-methyl-2,3-dihydro-1H-benzo[e][1,4]diazepine 
• 102428-90-0 1-methyl-2-<<<<2(S)-(methoxycarbonyl)-3-phenyl>propanoyl>amino>methyl>-5-(2'-fluorophenyl)-2,3-dihydro-1H-1,4-benzodiazepine 
• 123903-91-3 N'-N-Diethyl-N'-[5-(2-fluoro-phenyl)-1-methyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-ylmethyl]-methanediamine 

Relevant articles and documents

1,4-Benzodiazepine and 1,5-benzodiazocines. VII. Synthesis and biological activity

Synthesis of a new class of 2,3,-dihydro-1H-1,4-benzodiazepines and of the corresponding 1,2,3,4-tetrahydro-1,5-benzodiazocines is described. The biological activity of the compounds is evaluated in vivo by measuring their inhibition of pentetrazole induced seizures and in vitro by determining their affinity for the benzodiazepine receptor. Comparison of both tests reveals differences between activity in vivo and in vitro which are discussed.