6173-35-9 Usage
Description
17β-Acetoxy-2α-broMo-5α-androstanone is a steroid analog that exhibits inhibitive effects on progesterone synthesis and the binding of dihydrotestosterone to receptor protein. It is a white solid with potential applications in various industries due to its unique chemical properties and biological activities.
Uses
Used in Pharmaceutical Industry:
17β-Acetoxy-2α-broMo-5α-androstanone is used as a pharmaceutical compound for its ability to inhibit progesterone synthesis and dihydrotestosterone binding. This makes it a potential candidate for the development of drugs targeting hormonal imbalances and conditions related to androgen excess, such as hirsutism, polycystic ovary syndrome (PCOS), and certain types of cancer.
Used in Research and Development:
In the field of research and development, 17β-Acetoxy-2α-broMo-5α-androstanone serves as a valuable tool for studying the mechanisms of steroid hormone action, receptor protein interactions, and the role of progesterone and dihydrotestosterone in various physiological processes. Its use in research can lead to a better understanding of these hormones and the development of novel therapeutic strategies.
Used in Steroid Chemistry:
As a steroid analog, 17β-Acetoxy-2α-broMo-5α-androstanone is used in the field of steroid chemistry for the synthesis of other steroidal compounds with potential applications in medicine, agriculture, and other industries. Its unique structure allows for the exploration of new chemical reactions and the development of novel steroidal molecules with tailored properties and functions.
Used in Hormone Regulation:
17β-Acetoxy-2α-broMo-5α-androstanone is used as a hormone regulator, particularly in the context of conditions where the balance of progesterone and dihydrotestosterone is disrupted. By inhibiting their synthesis and binding, this compound can help restore hormonal balance and alleviate symptoms associated with hormonal imbalances.
Check Digit Verification of cas no
The CAS Registry Mumber 6173-35-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,7 and 3 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6173-35:
(6*6)+(5*1)+(4*7)+(3*3)+(2*3)+(1*5)=89
89 % 10 = 9
So 6173-35-9 is a valid CAS Registry Number.
6173-35-9Relevant articles and documents
The Cephalostatins. 22. Synthesis of bis-steroidal pyrazine pyrones
Pettit, George R.,Moser, Bryan R.,Mendonca, Ricardo F.,Knight, John C.,Hogan, Fiona
, p. 1063 - 1069 (2012/10/29)
Cephalostatin 1 (1), a remarkably strong cancer cell growth inhibitory trisdecacyclic, bis-steroidal pyrazine isolated from the marine tube worm Cephalodiscus gilchristi, continues to be an important target for practical total syntheses and a model for the discovery of less complex structural modifications with promising antineoplastic activity. In the present study, the cephalostatin E and F rings were greatly simplified by replacement at C-17 with an α-pyrone (in 12), typical of the steroidal bufodienolides, and by a dihydro-γ- pyrone (in 16). The synthesis of pyrazine 12 from 5α- dihydrotestosterone (nine steps, 8% overall yield) provided the first route to a bis-bufadienolide pyrazine. Dihydro-γ-pyrone 16 was synthesized in eight steps from ketone 13. While only insignificant cancer cell growth inhibitory activity was found for pyrones 12 and 16, the results provided further support for the necessity of more closely approximating the natural D-F ring system of cephalostatin 1 in order to obtain potent antineoplastic activity.
