6173-64-4 Usage
Description
17,20:20,21-Bis(Methylenedioxy)pregn-4-en-3-one is a chemical compound derived from the pregnane family, characterized by the presence of two methylenedioxy groups at the 20th and 21st carbon positions. It is an important intermediate in the synthesis of various metabolites and has potential applications in the pharmaceutical industry due to its structural properties.
Uses
Used in Pharmaceutical Industry:
17,20:20,21-Bis(Methylenedioxy)pregn-4-en-3-one is used as an intermediate in the synthesis of metabolites for Cortisol (H714615). Its role in the synthesis process is crucial for the production of these metabolites, which can have various therapeutic applications, including the treatment of adrenal insufficiency and other related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 6173-64-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,7 and 3 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 6173-64:
(6*6)+(5*1)+(4*7)+(3*3)+(2*6)+(1*4)=94
94 % 10 = 4
So 6173-64-4 is a valid CAS Registry Number.
6173-64-4Relevant articles and documents
Synthesis of 3- and 21-monosulfates of [2,2,3β,4,4-2H 5]-tetrahydrocorticosteroids in the 5β-series as internal standards for mass spectrometry
Ikegawa, Shigeo,Nagae, Kaori,Mabuchi, Takayuki,Okihara, Rika,Hasegawa, Maki,Minematsu, Toshie,Iida, Takashi,Mitamura, Kuniko
experimental part, p. 1232 - 1240 (2011/11/06)
The 3- and 21-monosulfates of pentadeuterated 5β- tetrahydrocorticosteroides were synthesized, starting from cortisol and 11-deoxycotisol. The principal reactions used were (1) perdeuteration of the methylene groups adjacent to the 3-oxo group of 17,20:20,21-bismethylendioxy- 5β-3-ketosteroids with NaOD in CH3OD followed by stereoselective reduction with NaBD4, (2) sulfation of hydroxy groups with sulfur trioxide-trimethylamine complex, and (3) removal of the 17,20:20,21- bismethylendioxy group with hydrogen fluoride. The labeled compounds can be used as internal standards in liquid chromatography/mass spectrometry assays for clinical and biochemical studies.
