617689-07-3 Usage
Description
5-Methoxy-2-methyl benzeneboronic acid, also known as (5-Methoxy-2-methylphenyl)boronic acid, is an organic compound with the molecular formula C7H9BO3. It is a white crystalline solid that is soluble in water and has a characteristic aromatic smell. 5-Methoxy-2-methyl benzeneboronic acid is a derivative of benzeneboronic acid, featuring a methoxy group at the 5th position and a methyl group at the 2nd position. Its unique structure and properties make it a versatile building block in organic synthesis and a valuable intermediate in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
5-Methoxy-2-methyl benzeneboronic acid is used as a key intermediate in the synthesis of Phenyl-substituted Imidazopyridine Amides. These compounds have demonstrated potential in the treatment of various cardiovascular and other disorders, making them an important class of drugs in the pharmaceutical industry.
Used in Organic Synthesis:
In the field of organic synthesis, 5-Methoxy-2-methyl benzeneboronic acid serves as a valuable building block for the creation of a wide range of complex organic molecules. Its unique structure allows for various functional group transformations and reactions, such as Suzuki-Miyaura cross-coupling, which can be used to form carbon-carbon bonds with other organic compounds.
Used in Chemical Research:
5-Methoxy-2-methyl benzeneboronic acid is also utilized in chemical research as a model compound for studying the reactivity and properties of benzeneboronic acid derivatives. This helps researchers understand the fundamental chemistry of these compounds and develop new synthetic strategies and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 617689-07-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,1,7,6,8 and 9 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 617689-07:
(8*6)+(7*1)+(6*7)+(5*6)+(4*8)+(3*9)+(2*0)+(1*7)=193
193 % 10 = 3
So 617689-07-3 is a valid CAS Registry Number.
617689-07-3Relevant articles and documents
ENANTIOPURE TERPHENYLS WITH TWO ORTHO-ATROPISOMERIC AXES
-
, (2019/07/19)
Enantiopure terphenyl presenting two ortho-located chiral axes having the following structural formula (I) : their process of synthesis and their use as mono or bidentate ligands for asymmetric organometallic reactions, as organocatalysts, as chiral base
Fast and Tight Boronate Formation for Click Bioorthogonal Conjugation
Akgun, Burcin,Hall, Dennis G.
supporting information, p. 3909 - 3913 (2016/03/19)
A new click bioorthogonal reaction system was devised to enable the fast ligation (kON≈340 m-1 s-1) of conjugatable derivatives of a rigid cyclic diol (nopoldiol) and a carefully optimized boronic acid partner, 2-methyl-5-carboxymethylphenylboronic acid. Using NMR and fluorescence spectroscopy studies, the corresponding boronates were found to form reversibly within minutes at low micromolar concentration in water, providing submicromolar equilibrium constant (Keq≈105-106 m-1). Efficient protein conjugation under physiological conditions was demonstrated with model proteins thioredoxin and albumin, and characterized by mass spectrometry and gel electrophoresis.
