617714-43-9

Basic information

• Product Name: 4-Piperidineethanol, a-(1-methylethyl)-1-(phenylmethyl)-
• CAS NO: 617714-43-9
• Molecular Formula: C17H27NO
• Molecular Weight: 261.407
• Mol File: 617714-43-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Piperidineethanol, a-(1-methylethyl)-1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidineethanol, a-(1-methylethyl)-1-(phenylmethyl)-(617714-43-9)
• EPA Substance Registry System: 4-Piperidineethanol, a-(1-methylethyl)-1-(phenylmethyl)-(617714-43-9)

Safety Data

• Hazardous Substances Data: 617714-43-9(Hazardous Substances Data)

Upstream product

• 40110-55-2 ethyl 2-(1-benzylpiperidine-4-ylidene)acetate 
• 100-39-0 benzyl bromide 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 41661-47-6 piperidin-4-one 
• 920-39-8 isopropylmagnesium bromide 
• 71879-59-9 ethyl (1-benzylpiperidin-4-yl)acetate 

Downstream Products

• 617714-18-8 1-(1-benzyl-piperidin-4-ylmethyl)-2-methyl-propylamine 
• 617714-46-2 1-(1-benzyl-piperidin-4-yl)-3-methyl-butan-2-one 

Relevant articles and documents

Design and synthesis of novel CCR3 antagonists

As part of our investigation into the development of potent CCR3 antagonists, a series of piperidine analogues was designed and prepared. Exploration of the piperidine core examined both the basicity and the location of a nitrogen, as well as conformational variants. The bicyclo-piperidine 24c was found to be the most potent inhibitor of CCR3 with an IC50 of 0.0082 μM in the binding assay and 0.0024 μM in the chemotaxis assay.