618064-77-0

Basic information

• Product Name: 1-(4-(4-methoxyphenyl)thiazol-2-yl)-2-(3-phenylallylidene)hydrazine
• CAS NO: 618064-77-0
• Molecular Weight: 335.429
• Mol File: 618064-77-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-(4-methoxyphenyl)thiazol-2-yl)-2-(3-phenylallylidene)hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-(4-methoxyphenyl)thiazol-2-yl)-2-(3-phenylallylidene)hydrazine(618064-77-0)
• EPA Substance Registry System: 1-(4-(4-methoxyphenyl)thiazol-2-yl)-2-(3-phenylallylidene)hydrazine(618064-77-0)

Safety Data

• Hazardous Substances Data: 618064-77-0(Hazardous Substances Data)

Upstream product

• 5351-70-2 cinnamaldehyde thiosemicarbazone 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 

Relevant articles and documents

Synthesis, anti-bacterial and anti-fungal activities of some novel Schiff bases containing 2,4-disubstituted thiazole ring

A series of arylidene-2-(4-(4-methoxy/bromophenyl) thiazol-2-yl) hydrazines (4a-z) and 1-(4-(4-methoxy/bromophenyl) thiazol-2-yl)-2-cyclohexylidene/cyclopentylidene hydrazines (5a-b/6a-b) were synthesized, characterized and screened for their antimicrobial activities. The structures of synthesized compounds were established by spectroscopic (FT-IR, 1H NMR, 13C NMR, Mass) and elemental analyses. Both the anti-bacterial and anti-fungal activities with MIC values of compounds were evaluated. The results of anti-bacterial screening reveal that among all the compounds screened eight compounds showed moderate to good anti-bacterial activity while ten of the newly synthesized compounds displayed good to excellent anti-fungal activity. Among the tested compounds, the most effective compounds with MIC value in the range of 6.25-25 μg/ml are 4a, 4n, 4z, 5a, 5b, 6a and 6b against three fungal strains viz. Candida albicans, Cryptococcus neoformans and Aspergillus flavus.