61807-78-1

Basic information

• Product Name: (7S)-7-(Bromoacetylamino)-7-methoxy-3-[[(1-methyl-1H-tetrazole-5-yl)thio]methyl]cepham-3-ene-4-carboxylic acid
• Synonyms: (6R,7S)-7-Bromoacetylamino-7-methoxy-3-[(1-methyl-1H-tetrazol-5-ylthio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;(7S)-7-(Bromoacetylamino)-7-methoxy-3-[[(1-methyl-1H-tetrazole-5-yl)thio]methyl]cepham-3-ene-4-carboxylic acid
• CAS NO: 61807-78-1
• Molecular Formula: C₁₃H₁₅BrN₆O₅S₂
• Molecular Weight: 479.33
• Mol File: 61807-78-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (7S)-7-(Bromoacetylamino)-7-methoxy-3-[[(1-methyl-1H-tetrazole-5-yl)thio]methyl]cepham-3-ene-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (7S)-7-(Bromoacetylamino)-7-methoxy-3-[[(1-methyl-1H-tetrazole-5-yl)thio]methyl]cepham-3-ene-4-carboxylic acid(61807-78-1)
• EPA Substance Registry System: (7S)-7-(Bromoacetylamino)-7-methoxy-3-[[(1-methyl-1H-tetrazole-5-yl)thio]methyl]cepham-3-ene-4-carboxylic acid(61807-78-1)

Safety Data

• Hazardous Substances Data: 61807-78-1(Hazardous Substances Data)

Upstream product

• 56610-72-1 diphenylmethyl (6R,7S)-7-amino-7-methoxy-3-<<(1-methyl-1H-tetrazol-5-yl)thio>methyl>-Δ³-cephem-4-carboxylate 
• 70035-75-5 7-bromoacetamide-7-methoxy-3-(1-methyl-1H-5-tetrazolyl)thiomethyl-3-cephem-4-carboxylic acid diphenyl methyl ester 

Downstream Products

• 69712-56-7 cefotetan 

Relevant articles and documents

Preparation method for intermediate compound of cephamycin

The invention provides a preparation method for an intermediate compound of cephamycin. The preparation method comprises the following steps: in a solvent, carrying out an addition reaction and a hydrolysis reaction on 7beta-(halomethyl-methoxy)imino-7alpha-methoxy-3-(1-methyl-1H-tetrazole-5-ylthiomethyl)-3-cephem-4-carboxylic acid trimethylsilane ester and hydrogen halide so as to obtain the intermediate compound of the cephamycin. According to the invention, cheap and easily available hydrogen halide is used as a main reaction reagent to replace trimethyl halosilane, so generation of byproducts and wastewater is reduced; and the preparation method disclosed by the invention is simple, low in cost, low in wastewater yield, green and environmentally-friendly, and high in target product yield and purity.