6190-94-9

Basic information

• Product Name: 2,2-diethoxy-N-[(E)-pyridin-2-ylmethylidene]ethanamine
• CAS NO: 6190-94-9
• Molecular Formula: C₁₂H₁₈N₂O₂
• Molecular Weight: 222.2835
• Mol File: 6190-94-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 313.5°C at 760 mmHg
• Flash Point: 143.4°C
• Density: 1.01g/cm³
• Vapor Pressure: 0.000913mmHg at 25°C
• Refractive Index: 1.497
• CAS DataBase Reference: 2,2-diethoxy-N-[(E)-pyridin-2-ylmethylidene]ethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-diethoxy-N-[(E)-pyridin-2-ylmethylidene]ethanamine(6190-94-9)
• EPA Substance Registry System: 2,2-diethoxy-N-[(E)-pyridin-2-ylmethylidene]ethanamine(6190-94-9)

Safety Data

• Hazardous Substances Data: 6190-94-9(Hazardous Substances Data)

Usage

Derivative of

Pyridine

Usage

Synthesis of coordination polymers and metal-organic frameworks; building block in organic synthesis; potential applications in drug design and catalysis

Physical state

Colorless liquid

Odor

Characteristic

Health hazard

Moderate (potential irritant and narcotic effects on the respiratory system)

Handling and storage

Appropriate safety precautions required

Upstream product

• 1121-60-4 pyridine-2-carbaldehyde 
• 645-36-3 2,2-diethoxy-ethanamine 

Downstream Products

• 6957-15-9 N-(2,2-diethoxyethyl)pyridine-2-methylamine 

Relevant articles and documents

Convergent and Practical Synthesis of Fluorescent Triphenylamine Derivatives and Their Localization in Living Cells

In the search for new fluorescent triphenylamine (TP) derivatives, we studied the influence of the position and substitution of diverse heterocyclic substituents. A library of 10 fluorescent triphenylamines bearing either oxazoles or thiazoles and pyridiniums, substituted at different positions has been developed. The approach is based on a convergent C?H activation reaction between pyridine-oxazoles or pyridine-thiazoles and di-iodo triphenylamine. We showed that the nature and substitution pattern of the 5-membered- (oxazole, thiazole) or 6-membered heterocycle (pyridine) has a strong influence on their fluorescence properties and on their localization in living cells as they stain either the nucleus or mitochondria.