6191-98-6

Basic information

• Product Name: Propanoic acid, 3,3-diMethoxy-
• Synonyms: Propanoic acid, 3,3-diMethoxy-;3,3-Dimethoxypropionic acid
• CAS NO: 6191-98-6
• Molecular Formula: C₅H₁₀O₄
• Molecular Weight: 134.1305
• Mol File: 6191-98-6.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Propanoic acid, 3,3-diMethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 3,3-diMethoxy-(6191-98-6)
• EPA Substance Registry System: Propanoic acid, 3,3-diMethoxy-(6191-98-6)

Safety Data

• Hazardous Substances Data: 6191-98-6(Hazardous Substances Data)

Usage

Description

Propanoic acid, 3,3-dimethoxyis a chemical compound with the molecular formula C5H10O4. It is a derivative of propanoic acid, a carboxylic acid, with two methoxy (CH3O) groups attached to the third carbon atom. Propanoic acid, 3,3-dimethoxyis known for its pleasant odor and taste, making it a versatile ingredient in various industries.

Uses

Used in Pharmaceutical Industry:
Propanoic acid, 3,3-dimethoxyis used as an active pharmaceutical ingredient for the development of medications due to its unique chemical properties and potential therapeutic effects.
Used in Fragrance Industry:
Propanoic acid, 3,3-dimethoxyis used as a fragrance ingredient for its pleasant odor, contributing to the creation of various scent profiles in perfumes, cosmetics, and other scented products.
Used in Flavoring Industry:
Propanoic acid, 3,3-dimethoxyis used as a flavoring agent for its agreeable taste, enhancing the flavor profiles of food and beverages.
Used as an Intermediate in Organic Synthesis:
Propanoic acid, 3,3-dimethoxyserves as an intermediate in the synthesis of various organic compounds, facilitating the production of a wide range of chemical products.
Used in Corrosion Inhibition:
Propanoic acid, 3,3-dimethoxyhas potential applications as a corrosion inhibitor, helping to protect materials from degradation in various industrial settings.
Used in Polymer Production:
Propanoic acid, 3,3-dimethoxyalso has potential uses as a component in polymer production, contributing to the development of new materials with specific properties for various applications.

Upstream product

• 7424-91-1 methyl 3,3-dimethoxypropionate 

Downstream Products

• 110450-43-6 4-methylphenyl 3,3-dimethoxypropanoate 
• 141498-77-3 Acetic acid 3-(3,3-dimethoxy-propionylamino)-4-methoxy-phenyl ester 
• 141498-81-9 Acetic acid 4-benzyloxy-3-(3,3-dimethoxy-propionylamino)-phenyl ester 
• 110450-42-5 4-methoxyphenyl 3,3-dimethoxypropanoate 
• 357428-20-7 N-(2-hydroxyphenyl)-3,3-dimethoxypropanamide 
• 110450-50-5 1-(2-hydroxy-5-methylphenyl)-3,3-dimethoxy-1-propanone 
• 110450-49-2 1-(2-hydroxy-5-methoxyphenyl)-3,3-dimethoxy-1-propanone 
• 921219-65-0 C₁₃H₁₉NO₃ 
• 921219-09-2 C₁₃H₁₉NO₄ 
• 921218-82-8 C₁₄H₂₁NO₄ 
• 921219-24-1 C₁₃H₁₈BrNO₃ 
• 1161829-64-6 N-(2-fluoro-3-methylphenyl)-3,3-dimethoxypropanamide 
• 1290048-05-3 4-[[(R)-2-(3-chloro-4-trifluoromethyl-phenylamino)-propyl]-(3,3-dimethoxy-propionyl)-amino]-butyric acid tert-butyl ester 
• 1311160-06-1 N-(2,5-dimethoxy-3-nitrophenyl)-3,3-dimethoxypropanamide 

Relevant articles and documents

TETRAHYDROPYRAZOLO-PYRAZINYL-DIHYDROIMIDAZOLONE OR TETRAHYDROPYRAZOLO-PYRIDINYL-DIHYDROIMIDAZOLONE COMPOUNDS AND METHODS OF USING SAME

The application relates to a compound of Formula (I) : or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which modulates the activity of GLP-1 receptor, a pharmaceutical composition comprising a compound of Formula (I), and a method of treating or preventing a disease in which GLP-1 receptor plays a role.

Development of the large-scale synthesis of tetrahydropyran glycine, a precursor to the HCV NS5A inhibitor BMS-986097

An efficient large-scale synthesis of acid 1, a penultimate precursor to the HCV NS5A inhibitor BMS-986097, along with the final API step are described. Three routes were devised for the synthesis of 1 at the various stages of the program. The third generation route, the one that proved scalable and is the main subject of this paper, features a one-step Michael addition of t-butyl 2-((diphenylmethylene)amino)acetate (24) to (E)-benzyl 4-(1-hydroxycyclopropyl)but-2-enoate (28) followed by cyclization and chiral separation to form 27c, the core skeleton of cap piece 1. The epimerization and chiral resolution of 27c followed by further synthetic manipulations involving the carbamate formation, lactone reduction and cyclization, afforded cyclopropyl pyran 1. A detailed study of diphenylmethane deprotection via acid hydrolysis as well as a key lactone to tetrahydropyran conversion, in order to avoid a side reaction that afforded an alternative cyclization product, are discussed. This synthesis was applied to the preparation of more than 100 g of the final API BMS-986097 for toxicology studies.

HEPATITIS C VIRUS INHIBITORS

The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.