61924-25-2 Usage
Description
3-Methylbenzyl isocyanate, also known as 1-(isocyanatomethyl)-3-methylbenzene, is an organic building block that features an isocyanate group. It is characterized by its clear colorless to yellow liquid appearance and has been studied for its vapor pressure properties.
Uses
Used in Chemical Synthesis:
3-Methylbenzyl isocyanate is used as a chemical intermediate for the synthesis of various compounds in the chemical industry. Its isocyanate group allows for the creation of a wide range of products, including polymers, pharmaceuticals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Methylbenzyl isocyanate is used as a building block for the development of new drugs. Its unique structure and reactivity make it a valuable component in the design and synthesis of novel therapeutic agents.
Used in Polymer Industry:
3-Methylbenzyl isocyanate is utilized as a monomer in the polymer industry for the production of polyurethanes and other isocyanate-based polymers. These materials are known for their versatility and are used in a variety of applications, such as coatings, adhesives, and elastomers.
Used in Research and Development:
Due to its unique chemical properties, 3-Methylbenzyl isocyanate is also used in research and development settings to explore new reactions and develop innovative applications in various fields, including materials science and biotechnology.
Check Digit Verification of cas no
The CAS Registry Mumber 61924-25-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,9,2 and 4 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 61924-25:
(7*6)+(6*1)+(5*9)+(4*2)+(3*4)+(2*2)+(1*5)=122
122 % 10 = 2
So 61924-25-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H9NO/c1-8-3-2-4-9(5-8)6-10-7-11/h2-5H,6H2,1H3
61924-25-2Relevant articles and documents
Process of preparing isocyanate compounds comprising non-chlorination derivatives and Composition thereof
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Paragraph 0149-0166, (2021/10/05)
The present invention relates to a process for producing xylylene diisocyanate. The present invention relates to a process for preparing isocyanates comprising the obtained non-chlorinated derivatives. In particular, the present invention relates to an isocyanate composition comprising an unchlorinated derivative obtained by the reduction reaction and a polymerizable composition including the same.
Orally Active β-Lactam Inhibitors of Leukocyte Elastase-1. Activity of 3,3-Diethyl-2-azetidinones
Shah, Shrenik K.,Dorn, Conrad P.,Finke, Paul E.,Hale, Jeffrey J.,Hagmann, William K.,et al.
, p. 3745 - 3754 (2007/10/02)
A thorough analysis of the mechanism of inhibition of human leukocyte elastase (HLE) by a monocyclic β-lactam and the mechanism of β-lactam hydrolysis led to the preparation of potent and highly stable inhibitors of HLE.This work led to the identification of 4--3,3-diethyl-1-carbonyl>-2-azetidinone (2) as the first orally active inhibitor of human leukocyte elastase (HLE).Analogs of 2 with different substituents on the urea N were synthesized and evaluated for their activity in vitro against HLE as well as in vivo in a hamster lung hemorrhage model.Compounds with a methyl or a methoxy group in the para position of the benzene ring were very potent in both assays.The results are discussed on the basis of the proposed model for the binding of this class of inhibitors to HLE and a possible mechanism of inhibition is presented.
