61925-77-7 Usage
Description
Boc-S-(4-methylbenzyl)-L-cysteine, also known as Boc-L-Cys(pMeBzl)-OH, is a derivative of the amino acid cystine. It is a white powder with unique chemical properties that make it valuable in various applications, particularly in the fields of chemical synthesis and peptide chemistry.
Uses
Used in Chemical Synthesis:
Boc-S-(4-methylbenzyl)-L-cysteine is used as a building block in chemical synthesis for the creation of complex molecules and compounds. Its unique structure allows for the formation of new bonds and the development of novel chemical entities.
Used in Peptide Chemistry:
In peptide chemistry, Boc-S-(4-methylbenzyl)-L-cysteine is utilized as a key component in the synthesis of peptides and proteins. Its incorporation into peptide sequences can influence the overall structure, stability, and function of the resulting peptide or protein, making it a valuable tool for researchers in this field.
Used in Pharmaceutical Industry:
Boc-S-(4-methylbenzyl)-L-cysteine is also used in the pharmaceutical industry for the development of new drugs and therapeutic agents. Its unique properties can be harnessed to create molecules with specific biological activities, potentially leading to the discovery of new treatments for various diseases and conditions.
Used in Research and Development:
In addition to its practical applications, Boc-S-(4-methylbenzyl)-L-cysteine is also used in research and development settings. Scientists and researchers can utilize this compound to study the fundamental principles of chemical reactions, peptide synthesis, and protein folding, contributing to the advancement of scientific knowledge in these areas.
Check Digit Verification of cas no
The CAS Registry Mumber 61925-77-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,9,2 and 5 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 61925-77:
(7*6)+(6*1)+(5*9)+(4*2)+(3*5)+(2*7)+(1*7)=137
137 % 10 = 7
So 61925-77-7 is a valid CAS Registry Number.
InChI:InChI=1/C16H23NO4S/c1-11-5-7-12(8-6-11)9-22-10-13(14(18)19)17-15(20)21-16(2,3)4/h5-8,13H,9-10H2,1-4H3,(H,17,20)(H,18,19)/t13-/m0/s1
61925-77-7Relevant articles and documents
A comprehensive one-pot synthesis of protected cysteine and selenocysteine SPPS derivatives
Flemer, Stevenson
, p. 1257 - 1264 (2015/04/14)
A proof-of-principle methodology is presented in which all commercially-available cysteine (Cys) and selenocysteine (Sec) solid phase peptide synthesis (SPPS) derivatives are synthesized in high yield from easily prepared protected dichalcogenide precursors. A Zn-mediated biphasic reduction process applied to a series of four bis-Nα-protected dichalcogenide compounds allows facile conversion to their corresponding thiol and selenol intermediates followed by insitu S- or Se-alkylation with various electrophiles to directly access twenty one known Cys and Sec SPPS derivatives. Most of these derivatives were able to be precipitated in crude form out of petroleum ether in sufficient purity for direct use as peptide building blocks. Subsequent incorporation of these derivatives into peptide models nicely illustrates their viability and applicability toward SPPS.
Two new procedures for the introduction of benzyl-type protecting groups for thiols
Richter, Lutz S.,Marsters Jr., James C.,Gadek, Thomas R.
, p. 1631 - 1634 (2007/10/02)
Two new methods for the benzylation of thiols are described: a) direct-S- alkylation with para-substituted benzylic cations; and b) reductive S- alkylations of 2-aminothiols. Both methods provide efficient routes for the introduction of benzyl-type protecting groups in high yields.
