619319-75-4

Basic information

• Product Name: N-(p-methoxybenzyl)-3,5-dimethylchloroacetanilide
• Synonyms: N-(p-methoxybenzyl)-3,5-dimethylchloroacetanilide
• CAS NO: 619319-75-4
• Molecular Weight: 317.815
• Mol File: 619319-75-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(p-methoxybenzyl)-3,5-dimethylchloroacetanilide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(p-methoxybenzyl)-3,5-dimethylchloroacetanilide(619319-75-4)
• EPA Substance Registry System: N-(p-methoxybenzyl)-3,5-dimethylchloroacetanilide(619319-75-4)

Safety Data

• Hazardous Substances Data: 619319-75-4(Hazardous Substances Data)

Upstream product

• 108-69-0 3,5-dimethylaminoaniline 
• 199435-31-9 3,5-dimethyl-N-(4-methoxybenzylidene)aniline 
• 123-11-5 4-methoxy-benzaldehyde 

Relevant articles and documents

Synthesis of substituted oxindoles from α-chloroacetanilides via palladium-catalyzed C - H functionalization

A novel method for the synthesis of oxindoles is described. In the presence of catalytic palladium acetate and 2-(di-tert-butylphosphino)biphenyl, α-chloroacetanilides are converted to oxindoles in good to excellent yields with high functional group compatibility using triethylamine as a stoichiometric base. The cyclization is highly regioselective, obviating the need for prefunctionalized arenes. Plausible mechanistic pathways for the reaction are discussed. Copyright