619323-22-7

Basic information

• Product Name: methyl 2-(3-bromophenyl)pent-4-enoate
• Synonyms: methyl 2-(3-bromophenyl)pent-4-enoate
• CAS NO: 619323-22-7
• Molecular Weight: 269.138
• Mol File: 619323-22-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl 2-(3-bromophenyl)pent-4-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(3-bromophenyl)pent-4-enoate(619323-22-7)
• EPA Substance Registry System: methyl 2-(3-bromophenyl)pent-4-enoate(619323-22-7)

Safety Data

• Hazardous Substances Data: 619323-22-7(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 619323-39-6 2-(3-bromophenyl)pent-4-enoic acid 
• 1878-67-7 3-Bromophenylacetic acid 
• 106-95-6 allyl bromide 
• 150529-73-0 methyl 2-(3-bromophenyl)acetatee 

Downstream Products

• 619323-39-6 2-(3-bromophenyl)pent-4-enoic acid 
• 691875-97-5 C₁₁H₁₁BrO₃ 
• 301854-30-8 3-(3-bromophenyl)-5-methyltetrahydrofuran-2-one 

Relevant articles and documents

GAMMA-AMINOAMIDE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

The present invention is directed to compounds of the formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R11, R12, W, X, and n are defined herein, which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.

3-Phenyl-5-methyl-2H,5H-furan-2-ones: Tuning antifungal activity by varying substituents on the phenyl ring

A series of racemic 3-phenyl-5-methyl-2H,5H-furan-2-ones related to a natural product, (-)incrustoporine, was synthesized, and their antifungal activity evaluated. The key structural feature, furanone ring, was closed via H2SO4-mediated cyclization of 2-phenylpent-4-enoic acids. The compounds displayed antifungal activity, especially against filamentous fungi. Expressed as the minimum inhibition concentration (MIC) in μmol/L, the activity of the most promising derivative against Absidia corymbifera matched that of ketoconazole (31.25 μmol/L). In terms of μg/mL, the substance was more active (7.6 μg/mL) than this standard antifungal drug (16.6 μg/mL). (C) 2000 Elsevier Science Ltd. All rights reserved.