61985-25-9

Basic information

• Product Name: 1-(1H-IMIDAZOL-4-YL)-ETHANONE HCL
• Synonyms: 1-(1H-IMIDAZOL-4-YL)-ETHANONE HCL;Ethanone, 1-(1H-imidazol-4-yl)- (9CI);Ethanone, 1-(1H-imidazol-5-yl)-;4-ethoxy-1H-imidazole;1-(1H-imidazol-4-yl)ethanone;1-(1H-iMidazol-4-yl)ethan-1-one;4-ACETYLIMIDAZOLE HYDROCHLORIDE;4-Acetyl-1H-imidazole
• CAS NO: 61985-25-9
• Molecular Formula: C₅H₆N₂O
• Molecular Weight: 110.11394
• Product Categories: ACETYLGROUP;pharmacetical
• Mol File: 61985-25-9.mol
• Article Data: 8

Chemical Properties

• Melting Point: 169-170℃
• Boiling Point: 329.422 °C at 760 mmHg
• Flash Point: 157.382 °C
• Appearance: /
• Density: 1.190
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 11.34±0.10(Predicted)
• CAS DataBase Reference: 1-(1H-IMIDAZOL-4-YL)-ETHANONE HCL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1H-IMIDAZOL-4-YL)-ETHANONE HCL(61985-25-9)
• EPA Substance Registry System: 1-(1H-IMIDAZOL-4-YL)-ETHANONE HCL(61985-25-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 61985-25-9(Hazardous Substances Data)

Usage

Description

1-(1H-Imidazol-4-yl)-ethanone HCl, also known as Imidazolone, is an organic compound derived from the essential oil of Mirabilis Jalapa root. It is a photochemical compound with a unique chemical structure that consists of an imidazole ring attached to an ethanone group. 1-(1H-Imidazol-4-yl)-ethanone HCl exhibits various properties that make it suitable for a range of applications across different industries.

Uses

Used in Pharmaceutical Industry:
1-(1H-Imidazol-4-yl)-ethanone HCl is used as an active pharmaceutical ingredient for its potential therapeutic effects. 1-(1H-Imidazol-4-yl)-ethanone HCl's unique structure allows it to interact with specific biological targets, making it a promising candidate for the development of new drugs to treat various diseases and medical conditions.
Used in Chemical Synthesis:
1-(1H-Imidazol-4-yl)-ethanone HCl serves as a key intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its versatile chemical structure enables it to be used as a building block for the creation of a wide range of molecules with diverse applications.
Used in Research and Development:
As a photochemical compound, 1-(1H-Imidazol-4-yl)-ethanone HCl is utilized in research laboratories for studying its properties, reactivity, and potential applications. Researchers can use this compound to explore new reaction pathways, develop innovative synthetic methods, and gain insights into the underlying mechanisms of various chemical processes.
Used in Analytical Chemistry:
1-(1H-Imidazol-4-yl)-ethanone HCl can be employed as a reference compound or a standard in analytical chemistry for the calibration of instruments and the development of new analytical methods. Its unique chemical structure and properties make it a valuable tool for the accurate determination of various parameters in chemical analysis.
Used in Material Science:
1-(1H-Imidazol-4-yl)-ethanone HCl's photochemical properties and unique structure make it a potential candidate for the development of new materials with specific properties. It can be used in the design and synthesis of advanced materials for applications in areas such as electronics, optics, and sensors.

InChI:InChI=1/C5H6N2O.ClH/c1-4(8)5-2-6-3-7-5;/h2-3H,1H3,(H,6,7);1H

Upstream product

• 100499-62-5 N-(5-methyl-4-isoxazolyl)formamide 
• 3465-72-3 (E)-3-(1H-imidazol-4-yl)propenoic acid 
• 2466-76-4 N-Acetylimidazole 
• 75-16-1 methylmagnesium bromide 
• 57090-88-7 1H-imidazole-4-carbonitrile 

Downstream Products

• 154148-92-2 2-(3-bromo-2-methylphenyl)-4,4-dimethyl-2-oxazoline 
• 189353-88-6 1-(3-benzyl-3H-imidazol-4-yl)ethanone 
• 148324-04-3 methyl 2-methyl-3-(1'-methyl-1'-(5''-imidazolyl)methyl)benzoate 
• 1026588-11-3 2-{3-[1-(3H-Imidazol-4-yl)-ethyl]-2-methyl-phenyl}-5,5-dimethyl-4,5-dihydro-oxazole 
• 850718-37-5 5-nitro-3-[1-(imidazol-4-yl)ethylidene]indolin-2-one 
• 116795-55-2 1-(1-triphenylmethyl-1H-imidazol-4-yl)-1-ethanone 
• 1394118-03-6 4-[1-(2-aminopyrimidin-4-yl)-3-methyl-1H-indazol-6-yl]-2-(1H-imidazol-4-yl)but-3-yn-2-ol 
• 1394120-03-6 4-[1-(2-aminopyrimidin-4-yl)-3-methylindazol-6-yl]-2-[1-(triphenylmethyl)imidazol-4-yl]but-3-yn-2-ol 
• 86347-14-0 medetomidine 
• 176721-04-3 (S)-dexmedetomidine-L-(+)-tartrate 
• 145108-58-3 (-)-(R)-4-(1-[2,3-dimethylphenyl]ethyl)-1H-imidazole hydrochloride 

Relevant articles and documents

Iron-catalyzed domino decarboxylation-oxidation of α,β-unsaturated carboxylic acids enabled aldehyde C-H methylation

A practical and general iron-catalyzed domino decarboxylation-oxidation of α,β-unsaturated carboxylic acids enabling aldehyde C-H methylation for the synthesis of methyl ketones has been developed. This mild, operationally simple method uses ambient air as the sole oxidant and tolerates sensitive functional groups for the late-stage functionalization of complex natural-product-derived and polyfunctionalized molecules.

SUBSTITUTED BIARYLS, PROCESS FOR THEIR MANUFACTURE AND USE THEREOF AS MEDICAMENTS

The present invention relates to compounds of general formula (I) wherein A, B, L, R1, R2, R3a and R3b are defined as in the specification, the tautomers, the enantiomers, the diastereomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable properties.

A GENERAL SYNTHESIS OF 4(5)-ACYLIMIDAZOLES FROM 4-ACYLAMINOISOXAZOLES.

2-Substituted-4(5)-acyl, 1,2-disubstituted 4-acyl and 1,2-disubstituted-5-acylimidazoles can be specifically prepared from 4-aminoisoxazoles.