620600-60-4Relevant articles and documents
Synthesis and biological evaluation of analogs of AAL(S) for use as ceramide synthase 1 inhibitors
Toop, Hamish D.,Don, Anthony S.,Morris, Jonathan C.
, p. 11593 - 11596 (2015/12/08)
A convergent synthesis to access hydrophobic tail analogs and head group modifications of AAL(S) is described. The analogs synthesised were evaluated for their ability to inhibit ceramide synthase 1 and for their cytotoxicity in K562 cells. Our results ha