62072-59-7Relevant articles and documents
Asymmetric enzymatic hydration of hydroxystyrene derivatives
Wuensch, Christiane,Gross, Johannes,Steinkellner, Georg,Gruber, Karl,Glueck, Silvia M.,Faber, Kurt
supporting information, p. 2293 - 2297 (2013/04/10)
More than one activity: Owing to their hydratase activity, phenolic acid decarboxylases catalyze the regio- and stereoselective addition of H 2O across the C=C double bond of hydroxystyrene derivatives yielding (S)-4-(1-hydroxyethyl)phenols with up to 82 % conversion and 71 % ee. Based on structure analysis and molecular docking simulations, a catalytic mechanism for this novel enzymatic reaction is proposed. Copyright