620970-68-5Relevant articles and documents
Antineoplastic agents. 561. Total synthesis of respirantin
Pettit, George R.,Smith, Thomas H.,Feng, Song,Knight, John C.,Tan, Rui,Pettit, Robin K.,Hinrichs, Peter A.
, p. 1073 - 1083 (2008/02/13)
Total synthesis of the 18-membered ring cyclodepsipeptide believed to be respirantin (1b) has been achieved. The key step in the synthesis is an intramolecular transesterification of the β-ketoester alcohol 6 to afford the protected macrocycle 5. The synt
