6217-61-4 Usage
General Description
(5-methyl)dithiouracil is a chemical compound with the molecular formula C5H6N2S2. It is a derivative of uracil and contains a methyl group and two thiol groups. (5-methyl)dithiouracil is known for its potential application in pharmaceutical research, particularly in the development of antithyroid drugs. It has been studied for its ability to inhibit the production of thyroid hormones, making it a potential candidate for the treatment of hyperthyroidism. Additionally, (5-methyl)dithiouracil has been investigated for its antioxidant and anti-inflammatory properties, which may have implications for the development of new therapeutic agents. Further research is needed to fully understand the potential uses and mechanisms of action of this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 6217-61-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,1 and 7 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6217-61:
(6*6)+(5*2)+(4*1)+(3*7)+(2*6)+(1*1)=84
84 % 10 = 4
So 6217-61-4 is a valid CAS Registry Number.
InChI:InChI=1/C5H6N2S2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)
6217-61-4Relevant articles and documents
Compounds
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Page/Page column 26; 27; 28, (2016/05/11)
Pyrimidone compounds of formula (I): are inhibitors of the enzyme Lp-PLA2 and are of use in treating atherosclerosis.
A thionation process and a thionating agent
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Page/Page column 13, (2012/08/14)
A process for transforming a group >C=O (I) in a compound into a group >C=S (II) or into a tautomeric form of group (II) in a reaction giving a thionated reaction product, by use of crystalline P2S5·2 C5H5N as a thionating agent. A thionating agent which is crystalline P2S5·2 C5H5N.
A Rapid and Efficient Synthesis of Sulfur Analogues of Pyrimidine Bases
Lapucha, Andrzej R.
, p. 256 - 258 (2007/10/02)
An improved procedure for thionation of some natural pyrimidine bases with tetraphosphorus decasulfide/sodium hydrogen carbonate is reported.Some substituted uracils and 2-thiouracils were converted into a series of analogues in which the oxygen at position 4 was replaced by sulfur atom.The advantage of this method of thionation over the older procedures is based on the tetraphosphorus decasulfide/sodium hydrogen carbonate mixture giving rise to excellent yields and simplified isolation of the desired pure products.
