62236-09-3

Basic information

• Product Name: 1-(5-AMINO-2-PHENYL-[1,3,4]THIADIAZOL-3-YL)-ETHANONE
• Synonyms: 1-(5-AMINO-2-PHENYL-[1,3,4]THIADIAZOL-3-YL)-ETHANONE;4-Acetyl-5-phenyl-4,5-dihydro-1,3,4-thiadiazol-2-amine;1-(5-amino-2-phenyl-2H-1,3,4-thiadiazol-3-yl)ethanone
• CAS NO: 62236-09-3
• Molecular Formula: C₁₀H₁₁N₃OS
• Molecular Weight: 221.28
• Mol File: 62236-09-3.mol
• Article Data: 1

Chemical Properties

• Melting Point: 160-161 °C
• Boiling Point: 378.1°C at 760 mmHg
• Flash Point: 182.5°C
• Appearance: /
• Density: 1.38g/cm³
• Vapor Pressure: 6.44E-06mmHg at 25°C
• Refractive Index: 1.688
• PKA: 0.56±0.40(Predicted)
• CAS DataBase Reference: 1-(5-AMINO-2-PHENYL-[1,3,4]THIADIAZOL-3-YL)-ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-AMINO-2-PHENYL-[1,3,4]THIADIAZOL-3-YL)-ETHANONE(62236-09-3)
• EPA Substance Registry System: 1-(5-AMINO-2-PHENYL-[1,3,4]THIADIAZOL-3-YL)-ETHANONE(62236-09-3)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 62236-09-3(Hazardous Substances Data)

Usage

Explanation

The compound is composed of 11 carbon atoms, 9 hydrogen atoms, 3 nitrogen atoms, 1 oxygen atom, and 1 sulfur atom.

Explanation

The compound contains a thiadiazole ring, which is a five-membered ring with two nitrogen atoms and one sulfur atom.

Explanation

The compound has an amino group (-NH2) attached to the thiadiazole ring and a phenyl group (C6H5) attached to the amino group.

Explanation

Due to its unique structure, the compound is used as a building block or intermediate in the synthesis of various organic compounds and has potential applications in the development of new drugs.
5. Potential Pharmacological and Biological Activities

Explanation

The compound's structure may provide it with specific pharmacological and biological properties, making it a valuable research tool for studying chemical and biological processes.

Explanation

The compound's unique structure and potential pharmacological and biological activities suggest that it could be used in the development of new drugs targeting various diseases or conditions.

Explanation

As a thiadiazole derivative with an amino and phenyl group, the compound can be used as a research tool to investigate the mechanisms of various chemical and biological processes, potentially leading to a better understanding of these processes and the development of new therapeutic strategies.

Chemical Structure

Thiadiazole derivative

Functional Groups

Amino group and phenyl group

Applications

Organic synthesis and pharmaceutical research

Development of New Drugs

Possible applications

Research Tool

Study of chemical and biological processes

InChI:InChI=1/C10H11N3OS/c1-7(14)13-9(15-10(11)12-13)8-5-3-2-4-6-8/h2-6,9H,1H3,(H2,11,12)/t9-/m1/s1

Upstream product

• 62236-01-5 2-(Acetamido)-4-acetyl-5-phenyl-Δ²-1,3,4-thiadiazoline 
• 1627-73-2 1-benzylidene thiosemicarbazide 

Downstream Products

• 72926-09-1 4-Acetyl-5-phenyl-2-(propionamido)-Δ²-1,3,4-thiadiazoline 
• 1157-84-2 1-benzylidene-2-(2,4-dinitrophenyl)hydrazone 
• 111862-69-2 4-Acetyl-2-(4-dimethylaminophenylazo)-5-phenyl-4,5-dihydro-1,3,4-thiadiazole 
• 72926-08-0 4-Acetyl-2-(deuterioacetamido)-5-phenyl-Δ²-1,3,4-thiadiazoline 
• 2002-03-1 2-amino-5-phenyl-1,3,4-thiadiazole 

Relevant articles and documents

Synthesis of 4-Acyl-2-(acylamino)-Δ2-1,3,4-thiadiazolines and 4-Acyl-2-amino-Δ2-1,3,4-thiadiazolines by Acylation of Thiosemicarbazones

Acylation of aldehyde and ketone thiosemicarbazones (2) with acid anhydrides or acid chlorides gave 4-acyl-2-(acylamino)-Δ2-1,3,4-thiadiazolines (3) in good yields.Treatment of 3 with hydrazine hydrate furnished the 2-amino derivatives (4).The 4-methylthiosemicarbazone of benzaldehyde underwent a similar cyclization with acetic anhydride to furnish the corresponding 2-(acetylmethylamino)thiadiazoline.