622403-42-3Relevant articles and documents
New efficient synthesis of 2-aryloxy-4(3H)-quinazolinones
Ding, Ming-Wu,Yang, Shang-Jun,Fu, Bo-Qiao
, p. 389 - 392 (2004)
2-Aryloxy-4(3H)-quinazolinones 5 were synthesized from cyclization of carbodiimides 2 with various phenols in presence of catalytic solid potassium carbonate in satisfactory yields.
Novel 4(3H)-Quinazolinone Derivatives Containing an Isoxazole Moiety: Design, Synthesis, and Bioactivity Evaluation
Xiang, Wang,Cheng-hao, Tang,Guo-lan, Wei,Jie-feng, Long
, p. 3220 - 3226 (2017/10/06)
The aim of the present study is to design and synthesize a series of novel 4(3H)-quinazolinone derivatives containing an isoxazole moiety and evaluate their antifungal activity against Gibberella zeae (G. zeae), Fusarium oxysporum (F. oxysporum), Cytospor
Functionalized carbodiimide mediated synthesis of 2,3-disubstituted quinazolin-4(3 H)-ones via the tandem strategy of C-nucleophilic addition and intramolecular NH-substitution cyclization
Nakano, Hayato,Kutsumura, Noriki,Saito, Takao
supporting information, p. 3179 - 3184 (2012/11/14)
A facile synthesis of quinazolin-4(3H)-ones possessing carbon substituents at positions 2 and 3 has been developed. Key to the synthesis is a tandem strategy involving introduction of a 2-substituent and construction of the quinazolinone framework via C-nucleophilic addition to the carbodiimide cumulenic carbon followed by intramolecular nucleophilic substitution by the newly formed NH moiety at the proximal ester group.