62254-97-1

Basic information

• Product Name: 1H-Imidazole-4,5-dicarboxamide, N,N'-dibutyl-
• CAS NO: 62254-97-1
• Molecular Formula: C13H22N4O2
• Molecular Weight: 266.343
• Mol File: 62254-97-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Imidazole-4,5-dicarboxamide, N,N'-dibutyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole-4,5-dicarboxamide, N,N'-dibutyl-(62254-97-1)
• EPA Substance Registry System: 1H-Imidazole-4,5-dicarboxamide, N,N'-dibutyl-(62254-97-1)

Safety Data

• Hazardous Substances Data: 62254-97-1(Hazardous Substances Data)

Upstream product

• 59157-06-1 4H,9H-diimidazo<1,5-a; 1',5'-d>pyrazine-5,10-dione-1,6-dicarboxylic dichloride 
• 109-73-9 N-butylamine 
• 100-46-9 benzylamine 

Relevant articles and documents

An improved method for the synthesis of dissymmetric N,N′-disubstituted imidazole-4,5-dicarboxamides

Symmetrically and dissymmetrically disubstituted imidazole-4,5-dicarboxamides (I45DCs) have diverse bioactivities and therefore represent useful small molecules for lead structure identification in drug discovery. For this reason, an improved synthesis was developed as a first step in the preparation of greater numbers of analogues. The method involves the transformation of imidazole-4,5-dicarboxylic acid into dissymmetrically disubstituted I45DCs in four steps and in a minimum yield of 51%. This reflects an overall reduction of one synthetic step and a greater than 30% improvement in yield over the known method.