62284-31-5

Basic information

• Product Name: Quinazoline, 2-(phenylmethyl)-
• Synonyms: 2-benzyl-quinazoline;2-Benzylchinazolin;Quinazoline,2-(phenylmethyl)
• CAS NO: 62284-31-5
• Molecular Formula: C15H12N2
• Molecular Weight: 220.274
• Mol File: 62284-31-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Quinazoline, 2-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Quinazoline, 2-(phenylmethyl)-(62284-31-5)
• EPA Substance Registry System: Quinazoline, 2-(phenylmethyl)-(62284-31-5)

Safety Data

• Hazardous Substances Data: 62284-31-5(Hazardous Substances Data)

Upstream product

• 5344-90-1 2-Aminobenzyl alcohol 
• 140-29-4 phenylacetonitrile 
• 4403-69-4 2-amino-1-benzylamine 
• 122-78-1 phenylacetaldehyde 
• 39696-31-6 2-benzyl-3,4-dihydroquinazoline 
• 85690-42-2 2-benzyl-4(3H)-quinazolinethione 
• 1555-80-2 phenylacetic anhydride 
• 529-23-7 o-aminobenzaldehyde 
• 6141-13-5 2-chloroquinazoline 
• 536-74-3 phenylacetylene 

Downstream Products

• 4765-56-4 glycosminine 

Relevant articles and documents

A facile access to: N -sulfonylthioimidates and their use for the transformation to 3,4-dihydroquinazolines

N-Sulfonylthioimidates can be efficiently synthesized through one-pot three-component coupling of terminal alkynes, sulfonyl azides, and thiols by using a copper(i) catalyst in the presence of 4-dimethylaminopyridine. The proposed reaction is characterized by mild reaction conditions and tolerance of diverse functional groups. Additionally, the crucial pharmacophore of 3,4-dihydroquinazolines was synthesized using a one-pot synthetic strategy from N-sulfonylthioimidates. This journal is

A facile and versatile protocol for the one-pot PhI(OAc)2 mediated divergent synthesis of quinazolines from 2-aminobenzylamine

In this present work iodobenzenediacetate (PIDA) has been found to be the key reagent in absence or presence of catalytic amount of molecular iodine (I2)/zinc chloride (ZnCl2) to construct quinazoline scaffold from 2-aminobenzylamine and a variety of easily available aldehydes, aryl and aliphatic amines, aliphatic and aryl alcohols and nitriles. This protocol provides mild and robust conditions along with great versatility to synthesize 2-substituted quinazolines from diverse starting materials in good to excellent yields. The developed protocol is also well applicable to reactants containing ease to oxidation prone functional groups.

STUDIES ON 4-QUINAZOLINONES. PART IX. RANEY NICKEL DESULPHURISATION OF 4-THIOQUINAZOLINES: ALUMINA CATALYSED HYDRATION OF 1,4- AND 3,4-DIHYDROQUINAZOLINES

A number of 2-substituted 3,4-dihydroquinazolines and 1,2-disubstituted 1,4-dihydroquinazolines but not the 3-mono or 2,3-disubstituted derivatives, prepared by Raney nickel desulphurisation of the corresponding 4-thioquinazolines (IV), underwent unusual