623143-78-2Relevant articles and documents
Novel tetrahydropyran-based peptidomimetics from a bioisosteric transformation of a tripeptide. Evidence of their activity at melanocortin receptors
Mazur, Adam W.,Kulesza, Anna,Mishra, Rajesh K.,Cross-Doersen, Doreen,Russell, Anne F.,Ebetino, Frank H.
, p. 3053 - 3063 (2007/10/03)
We have prepared novel peptidomimetics based on a 2,4,6-trisubstituted tetrahydropyran. This scaffold was constructed in an isosteric transformation using conceptual constraints imposed on a tripeptide moiety involving Oi′-Ci+1γ