62358-81-0

Basic information

• Product Name: Benzene, 1-(bromomethyl)-3-chloro-5-methyl-
• Synonyms: 3-chloro-5-methylbenzylbromide;3-chloro-5-methylbenzyl bromide;1-Bromomethyl-3-chloro-5-methyl-benzene;3-chloro-5-methyl-benzyl bromide
• CAS NO: 62358-81-0
• Molecular Formula: C8H8BrCl
• Molecular Weight: 219.509
• Mol File: 62358-81-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(bromomethyl)-3-chloro-5-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(bromomethyl)-3-chloro-5-methyl-(62358-81-0)
• EPA Substance Registry System: Benzene, 1-(bromomethyl)-3-chloro-5-methyl-(62358-81-0)

Safety Data

• Hazardous Substances Data: 62358-81-0(Hazardous Substances Data)

Upstream product

• 128-08-5 N-Bromosuccinimide 
• 556-97-8 1-chloro-3,5-dimethylbenzene 

Downstream Products

• 62358-62-7 2-(3-Chloro-5-methyl-benzyl)-malonic acid dimethyl ester 
• 56961-33-2 3-Chloro-5-Methylbenzoic Acid 
• 103426-20-6 3-chloro-5-methylbenzaldehyde 
• 62358-63-8 3-(3-Chloro-5-methyl-phenyl)-propionic acid 
• 62358-73-0 5-chloro-7-methyl-2,3-dihydro-1H-inden-1-one 
• 62358-66-1 4-(3-Chloro-5-methyl-phenyl)-butyronitrile 
• 62358-65-0 Methanesulfonic acid 3-(3-chloro-5-methyl-phenyl)-propyl ester 
• 62358-64-9 3-(3-Chloro-5-methyl-phenyl)-propan-1-ol 

Relevant articles and documents

Inhibitors of Serine Proteases

The present invention relates to compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention.

INHIBITORS OF SERINE PROTEASES FOR THE TREATMENT OF HCV INFECTIONS

The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt thereof. These compounds inhibit serine protease, particularly the hepatitis C virus NS3-NS4A protease.

AMINO ACID DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS

There is provided compounds of formula I, wherein R 1, R 2, R 3, R x, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required as in thrombosis or as anticoagulants.